Shopping Cart

Your shopping cart is currently empty

Tylosin

Name: Tylosin
Brand: TargetMol
SKU: T1003
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T1003Cas No. 1401-69-0

Alias Tylosine, Tylosin A, Tylocine, Fradizine

Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.

Tylosin

Copy Product Info

😃Good

Catalog No. T1003Alias Tylosine, Tylosin A, Tylocine, FradizineCas No. 1401-69-0

Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$46	-	In Stock
50 mg	$59	-	In Stock
100 mg	$72	-	In Stock
500 mg	$176	-	In Stock
1 mL x 10 mM (in DMSO)	$30	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Color:Yellow

Resource Download

COA HNMR MS

Product Introduction

Bioactivity

Description	Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.
In vivo	Tylosin and its phosphate and tartrate salts are used in pigs, cattle and poultry for the treatment of infections caused by organisms sensitive to tylosin. They mav be administered to calves oralv in the milk renlacer at a dose ot 40 moiko body weight (bw) and to cattle, by intramuscular injection, at a dose of 4-10 mg/kg bw. It may be administered in the drinking-water af a dose of 25 mg/kg bw, in the feed at a dose of 3-7 mg/kg bw or by intramuscularl injection at a dose of 2-10 mg/kg bw. Tylosin is administered to poultry in thel drinking-water at a dose equivalent to 75 mg/kg bw. It is used primarily in thel treatment of chronic respiratory diseasecomplex in chickens and infectioussinusitis in turkeys caused by Mycoplasma gallisepticum.
Synonyms	Tylosine, Tylosin A, Tylocine, Fradizine

Chemical Properties

Molecular Weight	916.10
Formula	C₄₆H₇₇NO₁₇
Cas No.	1401-69-0
Smiles	[H][C@@]1(C[C@@](C)(O)[C@@H](O)[C@H](C)O1)O[C@@H]1[C@@H](C)O[C@@]([H])(O[C@H]2[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(\C)=C\[C@H](CO[C@@H]3O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]3OC)[C@@H](CC)OC(=O)C[C@@H](O)[C@@H]2C)[C@H](O)[C@H]1N(C)C
Relative Density.	1.1424 g/cm3 (Estimated)

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 91 mg/mL (99.33 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (3.6 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0916 mL	5.4579 mL	10.9158 mL	54.5792 mL
5 mM	0.2183 mL	1.0916 mL	2.1832 mL	10.9158 mL
10 mM	0.1092 mL	0.5458 mL	1.0916 mL	5.4579 mL
20 mM	0.0546 mL	0.2729 mL	0.5458 mL	2.7290 mL
50 mM	0.0218 mL	0.1092 mL	0.2183 mL	1.0916 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc