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BDM31343 (Synonyms: BDM 31343)

Catalog No. T71649 Copy Product Info
Purity: 99.89%
🥰Excellent
BDM31343, an EthR inhibitor in Mycobacterium tuberculosis, enhances the antimicrobial activity of ethionamide with nanomolar potency, while improving solubility and metabolic stability.

BDM31343

Copy Product Info
🥰Excellent
Catalog No. T71649
Synonyms BDM 31343

BDM31343, an EthR inhibitor in Mycobacterium tuberculosis, enhances the antimicrobial activity of ethionamide with nanomolar potency, while improving solubility and metabolic stability.

BDM31343
Cas No. 1001468-07-0
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$293-In Stock
5 mg$722-In Stock
10 mg$987-In Stock
25 mg$1,520-In Stock
50 mg$1,980-In Stock
100 mg$2,500-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.89%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
BDM31343, an EthR inhibitor in Mycobacterium tuberculosis, enhances the antimicrobial activity of ethionamide with nanomolar potency, while improving solubility and metabolic stability.
SynonymsBDM 31343
Chemical Properties
Molecular Weight302.35
FormulaC14H14N4O2S
Cas No.1001468-07-0
SmilesO=C(CC#N)N1CCC(CC1)c1nc(no1)-c1cccs1
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 6.06 mg/mL (20.04 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3074 mL16.5371 mL33.0743 mL165.3713 mL
5 mM0.6615 mL3.3074 mL6.6149 mL33.0743 mL
10 mM0.3307 mL1.6537 mL3.3074 mL16.5371 mL
20 mM0.1654 mL0.8269 mL1.6537 mL8.2686 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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