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Ginsenoside Re

Name: Ginsenoside Re
Brand: TargetMol
SKU: T2872
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2872Cas No. 52286-59-6

Alias Sanchinoside Re, Panaxoside Re, Ginsenoside B2, Chikusetsusaponin Ivc

Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.

Ginsenoside Re

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Purity: 99.78%

Catalog No. T2872Alias Sanchinoside Re, Panaxoside Re, Ginsenoside B2, Chikusetsusaponin IvcCas No. 52286-59-6

Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$30	In Stock	In Stock
5 mg	$43	In Stock	In Stock
10 mg	$61	In Stock	In Stock
25 mg	$98	In Stock	In Stock
50 mg	$148	In Stock	In Stock
100 mg	$218	In Stock	In Stock
200 mg	$323	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$63	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.78%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Ginsenoside Re AI Summary

Ginsenoside Re exhibits a range of bioactivities with potential therapeutic applications. It demonstrates significant hepatoprotective properties in mouse hepatocytes, enhancing cell survival rates by 36.4% to 52.4% and inhibiting cell death by 21.1% to 74.3% in response to D-galactosamine/TNFalpha challenge. Additionally, the compound offers robust protection against D-galactosamine/LPS-induced liver injury in mice, reducing serum alanine transaminase and aspartate transaminase levels by 92.0% and 90.0%, respectively, when administered at 100 mg/kg. It has an IC50 value of 119,000 nM for inhibiting cell death. In the domain of virology, Ginsenoside Re exhibits inhibitory activity against HIV1 reverse transcriptase with an IC50 value greater than 200.0 μg/mL. Furthermore, it induces neurite outgrowth in human SK-N-SH cells, showing an activity level of 83.5% at 100 μM after 5 days, suggesting potential applications in nerve regeneration. In cardiovascular studies, Ginsenoside Re demonstrates cardioprotective effects in a rat ischemia-reperfusion injury model, reducing myocardial infarct size and the area at risk when administered intravenously at 20 mg/kg. Surprisingly, it shows no significant inhibition of human DNA topoisomerase 1 or 2 activity, suggesting its mechanisms do not interfere with these essential enzymes. Collectively, Ginsenoside Re shows promise in hepatoprotection, antiviral activity, nerve regeneration, and cardioprotection, warranting further investigation into its therapeutic potential and mechanisms of action..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.
Synonyms	Sanchinoside Re, Panaxoside Re, Ginsenoside B2, Chikusetsusaponin Ivc

Chemical Properties

Molecular Weight	947.15
Formula	C₄₈H₈₂O₁₈
Cas No.	52286-59-6
Smiles	[H][C@@]1(CC[C@]2(C)[C@]1([H])CC[C@]1([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])[C@H](C[C@@]21C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)[C@](C)(CCC=C(C)C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Relative Density.	1.38 g/cm3

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (263.95 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (2.11 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0558 mL	5.2790 mL	10.5580 mL	52.7899 mL
5 mM	0.2112 mL	1.0558 mL	2.1116 mL	10.5580 mL
10 mM	0.1056 mL	0.5279 mL	1.0558 mL	5.2790 mL
20 mM	0.0528 mL	0.2639 mL	0.5279 mL	2.6395 mL
50 mM	0.0211 mL	0.1056 mL	0.2112 mL	1.0558 mL
100 mM	0.0106 mL	0.0528 mL	0.1056 mL	0.5279 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Ginsenoside Re

Ginsenoside Re

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