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ML162-yne

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Catalog No. T203712Cas No. 2883115-46-4

ML162-yne is an effective GPX4 inhibitor and affinity probe containing an alkyne group capable of click chemistry reactions with azide-containing molecules.

ML162-yne

ML162-yne

😃Good
Purity: 99.53%
Catalog No. T203712Cas No. 2883115-46-4
ML162-yne is an effective GPX4 inhibitor and affinity probe containing an alkyne group capable of click chemistry reactions with azide-containing molecules.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$30-In Stock
5 mg$48-In Stock
10 mg$81-In Stock
25 mg$163-In Stock
50 mg$247-In Stock
100 mg$372-In Stock
1 mL x 10 mM (in DMSO)$53-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.53%
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Product Introduction

Bioactivity
Description
ML162-yne is an effective GPX4 inhibitor and affinity probe containing an alkyne group capable of click chemistry reactions with azide-containing molecules.
Chemical Properties
Molecular Weight501.43
FormulaC25H22Cl2N2O3S
Cas No.2883115-46-4
SmilesO=C(NCCC=1C=CC=CC1)C(C=2SC=CC2)N(C(=O)CCl)C3=CC=C(OCC#C)C(Cl)=C3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (159.54 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9943 mL9.9715 mL19.9430 mL99.7148 mL
5 mM0.3989 mL1.9943 mL3.9886 mL19.9430 mL
10 mM0.1994 mL0.9971 mL1.9943 mL9.9715 mL
20 mM0.0997 mL0.4986 mL0.9971 mL4.9857 mL
50 mM0.0399 mL0.1994 mL0.3989 mL1.9943 mL
100 mM0.0199 mL0.0997 mL0.1994 mL0.9971 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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