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(R)-Zanubrutinib

🥰Excellent
Catalog No. T13447Cas No. 1691249-44-1
Alias (R)-BGB-3111

(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).

(R)-Zanubrutinib
Other Forms of (R)-Zanubrutinib:

(R)-Zanubrutinib

🥰Excellent
Purity: 99.55%
Catalog No. T13447Alias (R)-BGB-3111Cas No. 1691249-44-1
(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$33In StockIn Stock
5 mg$77In StockIn Stock
10 mg$143In StockIn Stock
25 mg$238In StockIn Stock
50 mg$358In StockIn Stock
100 mg$491-In Stock
200 mg$683-In Stock
1 mL x 10 mM (in DMSO)$82In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.55%
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Product Introduction

Bioactivity
Description
(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).
Targets&IC50
BTK:0.011 μM
Synonyms(R)-BGB-3111
Chemical Properties
Molecular Weight471.55
FormulaC27H29N5O3
Cas No.1691249-44-1
SmilesNC(=O)c1c2NCC[C@H](C3CCN(CC3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1
Relative Density.1.33 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 57.8 mg/mL (122.57 mM), Sonication is recommended.
Ethanol: < 1?mg/mL?(insoluble?or?slightly?soluble), insoluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1207 mL10.6033 mL21.2067 mL106.0333 mL
5 mM0.4241 mL2.1207 mL4.2413 mL21.2067 mL
10 mM0.2121 mL1.0603 mL2.1207 mL10.6033 mL
20 mM0.1060 mL0.5302 mL1.0603 mL5.3017 mL
50 mM0.0424 mL0.2121 mL0.4241 mL2.1207 mL
100 mM0.0212 mL0.1060 mL0.2121 mL1.0603 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ZanubrutinibBTKBGB-3111BGB3111BGB 3111
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