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Etoricoxib-d4

Name: Etoricoxib-d4
Brand: TargetMol
SKU: T11246
Price: 149 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11246Cas No. 1131345-14-6

Alias MK-0663 D4, L-791456 D4, Etoricoxib D4

Etoricoxib-d4 is a deuterated form of Etoricoxib. Etoricoxib is a synthetic non-steroidal anti-inflammatory compound, an orally available and selective COX-2 inhibitor with antipyretic, analgesic, and potential anticancer properties.

Etoricoxib-d4

🥰Excellent

Catalog No. T11246Alias MK-0663 D4, L-791456 D4, Etoricoxib D4Cas No. 1131345-14-6

Pack Size	Price	Availability	Quantity
1 mg	$149	In Stock

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Batch Information

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Purity:>99.99%

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COA LCMS

Product Introduction

Bioactivity

Description	Etoricoxib-d4 is a deuterated form of Etoricoxib. Etoricoxib is a synthetic non-steroidal anti-inflammatory compound, an orally available and selective COX-2 inhibitor with antipyretic, analgesic, and potential anticancer properties.
Synonyms	MK-0663 D4, L-791456 D4, Etoricoxib D4

Chemical Properties

Molecular Weight	362.87
Formula	C₁₈H₁₁D₄ClN₂O₂S
Cas No.	1131345-14-6
Smiles	ClC1=CC(=C(N=C1)C=2C=CC(C)=NC2)C3=C(C(=C(S(C)(=O)=O)C(=C3[2H])[2H])[2H])[2H]
Relative Density.	no data available
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (220.46 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7558 mL	13.7790 mL	27.5581 mL	137.7904 mL
5 mM	0.5512 mL	2.7558 mL	5.5116 mL	27.5581 mL
10 mM	0.2756 mL	1.3779 mL	2.7558 mL	13.7790 mL
20 mM	0.1378 mL	0.6890 mL	1.3779 mL	6.8895 mL
50 mM	0.0551 mL	0.2756 mL	0.5512 mL	2.7558 mL
100 mM	0.0276 mL	0.1378 mL	0.2756 mL	1.3779 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc