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L-Glutamic acid monosodium salt
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Catalog No. T6871Cas No. 142-47-2
Alias MSG, Monosodium glutamate, Glutavene, Glutacyl, Ajinomoto
L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
L-Glutamic acid monosodium salt
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Purity: 99.93%
Catalog No. T6871Alias MSG, Monosodium glutamate, Glutavene, Glutacyl, AjinomotoCas No. 142-47-2
L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 g | $30 | In Stock | In Stock | |
| 5 g | $40 | - | In Stock | |
| 10 g | $56 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.93%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor. |
| In vitro | Monosodium glutamate(MSG) induces apoptosis in human B cells. It has a more potent apoptotic effect in na?ve B cells compared to memory B cell population[3]. Low doses of L-monosodium glutamate promote neuronal growth and differentiation in vitro[4]. |
| In vivo | Daily L-Glutamic acid monosodium salt(MSG) dietary consumption reduces pancreatic β-cell mass and enhances hemorrhages and fibrosis, but does not affect glucose homeostasis. High dietary MSG intake may exert a negative effect on the pancreas and such effect might become functionally significant in the presence or susceptibility to diabetes or NaCl. Parenteral MSG causes various changes in pancreatic islets such as hypertrophy, hyperplasia, decrease in acinar cells, α-cells and somatostatin cells and increase in fibrosis[1]. MSG may have some deleterious effects on the testes of Wistar rats and by extension may contribute to the causes of male infertility[2]. |
| Cell Research | B cells are cultured with and with out increasing concentrations of MSG(1-100 mM) for 24 h. The number of early apoptotic cells and necrotic cells is determined using Annexin-V FITC/PI staining. (Only for Reference) |
| Synonyms | MSG, Monosodium glutamate, Glutavene, Glutacyl, Ajinomoto |
| Molecular Weight | 169.11 |
| Formula | C5H8NO4·Na |
| Cas No. | 142-47-2 |
| Smiles | [Na+].N[C@@H](CCC(O)=O)C([O-])=O |
| Relative Density. | 1.65 g/cm3. Temperature:20 °C.;1.65. Temperature:20 °C. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: < 1 mg/mL (insoluble or slightly soluble)  H2O: 115 mg/mL (680.03 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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