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Sulbactam

Name: Sulbactam
Brand: TargetMol
SKU: T1631
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1631Cas No. 68373-14-8

Alias CP45899

Sulbactam (CP45899) is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.

Sulbactam

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Purity: 99.32%

Catalog No. T1631Alias CP45899Cas No. 68373-14-8

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$38	In Stock	In Stock
100 mg	$50	In Stock	In Stock
200 mg	$58	In Stock	In Stock
500 mg	$92	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$47	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.32%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description

Synonyms

CP45899

Chemical Properties

Molecular Weight	233.24
Formula	C₈H₁₁NO₅S
Cas No.	68373-14-8
Smiles	[Na+].[H][C@@]12CC(=O)N1C(C([O-])=O)C(C)(C)S2(=O)=O
Relative Density.	1.62 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 43 mg/mL (184.36 mM), Sonication is recommended.

DMSO: 250 mg/mL (1071.86 mM), Sonication is recommended.

Ethanol: 44 mg/mL (188.65 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.57 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2874 mL	21.4371 mL	42.8743 mL	214.3715 mL
5 mM	0.8575 mL	4.2874 mL	8.5749 mL	42.8743 mL
10 mM	0.4287 mL	2.1437 mL	4.2874 mL	21.4371 mL
20 mM	0.2144 mL	1.0719 mL	2.1437 mL	10.7186 mL
50 mM	0.0857 mL	0.4287 mL	0.8575 mL	4.2874 mL
100 mM	0.0429 mL	0.2144 mL	0.4287 mL	2.1437 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc