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Toltrazuril (sulfone)

Name: Toltrazuril (sulfone)
Brand: TargetMol
SKU: T5052
Price: 46 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5052Cas No. 69004-04-2

Alias Toltrazuril sulfone, Ponazuril

Toltrazuril sulfone (Ponazuril) is an antiprotozoal agent that acts upon Coccidia parasites.

Toltrazuril (sulfone)

🥰Excellent

Purity: 98.84%

Catalog No. T5052Alias Toltrazuril sulfone, PonazurilCas No. 69004-04-2

Toltrazuril sulfone (Ponazuril) is an antiprotozoal agent that acts upon Coccidia parasites.

Pack Size	Price	Availability
10 mg	$46	In Stock
25 mg	$72	In Stock
50 mg	$97	In Stock
100 mg	$119	In Stock
1 mL x 10 mM (in DMSO)	$51	In Stock

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Batch Information

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Purity:98.84%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Toltrazuril sulfone (Ponazuril) is an antiprotozoal agent that acts upon Coccidia parasites.
In vivo	Afloqualone slightly increased the response during the alarm period in one out of 3 rats at 5, 10, and 20 mg/kg p.o., respectively.
Synonyms	Toltrazuril sulfone, Ponazuril

Chemical Properties

Molecular Weight	457.38
Formula	C₁₈H₁₄F₃N₃O₆S
Cas No.	69004-04-2
Smiles	Cc1cc(ccc1Oc1ccc(cc1)S(=O)(=O)C(F)(F)F)-n1c(=O)[nH]c(=O)n(C)c1=O
Relative Density.	1.507g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (109.32 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1864 mL	10.9318 mL	21.8637 mL	109.3183 mL
5 mM	0.4373 mL	2.1864 mL	4.3727 mL	21.8637 mL
10 mM	0.2186 mL	1.0932 mL	2.1864 mL	10.9318 mL
20 mM	0.1093 mL	0.5466 mL	1.0932 mL	5.4659 mL
50 mM	0.0437 mL	0.2186 mL	0.4373 mL	2.1864 mL
100 mM	0.0219 mL	0.1093 mL	0.2186 mL	1.0932 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc