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BRD4-IN-4

Name: BRD4-IN-4
Brand: TargetMol
SKU: T77339
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77339Cas No. 304685-40-3

BRD4-IN-4 is a selective BRD4 inhibitor with an IC50 value of 6.83 μM for BRD4.BRD4-IN-4 selectively inhibits the proliferation of the MV4-11 cell line and arrests the cells in G1 phase.BRD4-IN-4 can be used to study MLL leukemias.

BRD4-IN-4

🥰Excellent

Purity: 99.97%

Catalog No. T77339Cas No. 304685-40-3

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$31	In Stock	In Stock
25 mg	$50	In Stock	In Stock
50 mg	$74	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.97%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	BRD4-IN-4 is a selective BRD4 inhibitor with an IC50 value of 6.83 μM for BRD4.BRD4-IN-4 selectively inhibits the proliferation of the MV4-11 cell line and arrests the cells in G1 phase.BRD4-IN-4 can be used to study MLL leukemias.
Targets&IC50	BRD4:6.83 μM

Chemical Properties

Molecular Weight	330.4
Formula	C₁₇H₁₈N₂O₃S
Cas No.	304685-40-3
Smiles	CCN1C(=O)C2=CC=CC3=C(C=CC1=C23)S(=O)(=O)N1CCCC1
Color	Green
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (136.2 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0266 mL	15.1332 mL	30.2663 mL	151.3317 mL
5 mM	0.6053 mL	3.0266 mL	6.0533 mL	30.2663 mL
10 mM	0.3027 mL	1.5133 mL	3.0266 mL	15.1332 mL
20 mM	0.1513 mL	0.7567 mL	1.5133 mL	7.5666 mL
50 mM	0.0605 mL	0.3027 mL	0.6053 mL	3.0266 mL
100 mM	0.0303 mL	0.1513 mL	0.3027 mL	1.5133 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc