Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

NT160

🥰Excellent
Catalog No. T78709Cas No. 1418293-40-9
Alias NT 160

NT160 is a fluorinated radioactive compound, a potent class IIa histone deacetylase (HDAC) inhibitor, used in the study of neurological diseases.

NT160

NT160

🥰Excellent
Purity: 99.3%
Catalog No. T78709Alias NT 160Cas No. 1418293-40-9
NT160 is a fluorinated radioactive compound, a potent class IIa histone deacetylase (HDAC) inhibitor, used in the study of neurological diseases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$100In StockIn Stock
5 mg$247In StockIn Stock
10 mg$396-In Stock
25 mg$795-In Stock
50 mg$1,280-In Stock
100 mg$1,980-In Stock
1 mL x 10 mM (in DMSO)$272-In Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.3%
Contact us for more batch information

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity
Description
NT160 is a fluorinated radioactive compound, a potent class IIa histone deacetylase (HDAC) inhibitor, used in the study of neurological diseases.
Targets&IC50
HDAC7:1.0 nM, HDAC4:0.08 nM, HDAC5:1.2 nM, HDAC9:0.9 nM
In vitro
NT160 is a highly effective Class IIa HDAC inhibitor with an IC50 value of 0.046 μM.
NT160 showed very high inhibition on HDAC4, HDAC5, HDAC7 and HDAC9, with IC50 values of 0.08 nM, 1.2 nM, 1.0 nM and 0.9 nM, respectively. [1]
In vivo
NT160 was able to penetrate the blood-brain barrier and accumulate in the brains of mice. [1]
SynonymsNT 160
Chemical Properties
Molecular Weight418.41
FormulaC21H21F3N4O2
Cas No.1418293-40-9
SmilesC(F)(F)(F)C1=NC(=NO1)C2=CC=C(C(N[C@@H](CN(CC3=CC=CC=C3)C)C)=O)C=C2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (191.2 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (7.89 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3900 mL11.9500 mL23.9000 mL119.5000 mL
5 mM0.4780 mL2.3900 mL4.7800 mL23.9000 mL
10 mM0.2390 mL1.1950 mL2.3900 mL11.9500 mL
20 mM0.1195 mL0.5975 mL1.1950 mL5.9750 mL
50 mM0.0478 mL0.2390 mL0.4780 mL2.3900 mL
100 mM0.0239 mL0.1195 mL0.2390 mL1.1950 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy NT160 | purchase NT160 | NT160 cost | order NT160 | NT160 chemical structure | NT160 in vivo | NT160 in vitro | NT160 formula | NT160 molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.