Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NT160, a potent class-IIa HDAC inhibitor, exhibits an IC50 of 0.046 μM and has potential applications in central nervous system disease research [1].
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Description | NT160, a potent class-IIa HDAC inhibitor, exhibits an IC50 of 0.046 μM and has potential applications in central nervous system disease research [1]. |
Targets&IC50 | HDAC9:0.9 nM, HDAC7:1.0 nM, HDAC5:1.2 nM, HDAC4:0.08 nM |
In vitro | NT160 exhibits affinity for the class IIa HDAC4 isoform with an IC50 value of 0.046 μM [1]. It demonstrates potent inhibitory activity against HDAC4, HDAC5, HDAC7, and HDAC9, with IC50 values of 0.08 nM, 1.2 nM, 1.0 nM, and 0.9 nM, respectively [1]. |
Molecular Weight | 418.41 |
Formula | C21H21F3N4O2 |
CAS No. | 1418293-40-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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NT160 1418293-40-9 Chromatin/Epigenetic DNA Damage/DNA Repair HDAC inhibitor inhibit