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Todralazine hydrochloride

Name: Todralazine hydrochloride
Brand: TargetMol
SKU: T17111
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T17111Cas No. 3778-76-5

Alias Ecarazine hydrochloride

Todralazine hydrochloride (Ecarazine hydrochloride) is a β2AR blocker with antioxidant and free radical scavenging properties, making it suitable for anti-hypertensive research.

Todralazine hydrochloride

🥰Excellent

Purity: 99.91%

Catalog No. T17111Alias Ecarazine hydrochlorideCas No. 3778-76-5

Todralazine hydrochloride (Ecarazine hydrochloride) is a β2AR blocker with antioxidant and free radical scavenging properties, making it suitable for anti-hypertensive research.

Pack Size	Price	Availability
10 mg	$39	In Stock
25 mg	$59	In Stock
50 mg	$80	In Stock
1 mL x 10 mM (in DMSO)	$43	In Stock

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Batch Information

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Purity:99.91%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Todralazine hydrochloride (Ecarazine hydrochloride) is a β2AR blocker with antioxidant and free radical scavenging properties, making it suitable for anti-hypertensive research.
Synonyms	Ecarazine hydrochloride

Chemical Properties

Molecular Weight	268.7
Formula	C₁₁H₁₃ClN₄O₂
Cas No.	3778-76-5
Smiles	Cl.CCOC(=O)NNc1nncc2ccccc12
Relative Density.	1.328g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 14 mg/mL (52.10 mM), Sonication is recommended.

DMSO: 120 mg/mL (446.59 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7216 mL	18.6081 mL	37.2162 mL	186.0811 mL
5 mM	0.7443 mL	3.7216 mL	7.4432 mL	37.2162 mL
10 mM	0.3722 mL	1.8608 mL	3.7216 mL	18.6081 mL
20 mM	0.1861 mL	0.9304 mL	1.8608 mL	9.3041 mL
50 mM	0.0744 mL	0.3722 mL	0.7443 mL	3.7216 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0372 mL	0.1861 mL	0.3722 mL	1.8608 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc