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Nourseothricin sulfate

Name: Nourseothricin sulfate
Brand: TargetMol
SKU: T12248
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12248Cas No. 96736-11-7

Alias Streptothricin sulfate

Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic that inhibits protein biosynthesis in prokaryotic cells and significantly impedes the growth of eukaryotes, including fungi.

Nourseothricin sulfate

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Purity: 99.83%

Catalog No. T12248Alias Streptothricin sulfateCas No. 96736-11-7

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$39	In Stock	In Stock
10 mg	$63	In Stock	In Stock
25 mg	$107	In Stock	In Stock
50 mg	$163	In Stock	In Stock
100 mg	$263	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.83%

Appearance:Solid

Color:White

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COA LCMS

Product Introduction

Bioactivity

Description	Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic that inhibits protein biosynthesis in prokaryotic cells and significantly impedes the growth of eukaryotes, including fungi.
In vivo	Renal handling of Nourseothricin is characterized in experiments on renal cortical slices under various experimental conditions.?Following administration in vivo the renal tubular transport system for organic anions (p-aminohippurate, PAH) is not influenced by Nourseothricin.?There is a high degree of accumulation of Nourseothricin in renal cortical slices.?In contrast to PAH accumulation there is no influence of nitrogen atmosphere, simultaneous administration of PAH, probenecid or trishydroxyaminomethane on Nourseothricin accumulation.?Age dependent differences in Nourseothricin accumulation does not exist[1].
Synonyms	Streptothricin sulfate

Chemical Properties

Molecular Weight	1359.47
Formula	C₅₀H₉₄N₂₀O₂₂S
Cas No.	96736-11-7
Smiles	OS(O)(=O)=O.[H][C@]12NC(N[C@@H]3O[C@H](CO)[C@H](OC(N)=O)[C@@H](O)[C@H]3NC(=O)C[C@@H](N)CCCNC(=O)C[C@@H](N)CCCN)=N[C@]1([H])C(=O)NC[C@H]2O
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 250 mg/mL (183.9 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	0.7356 mL	3.6779 mL	7.3558 mL	36.7790 mL
5 mM	0.1471 mL	0.7356 mL	1.4712 mL	7.3558 mL
10 mM	0.0736 mL	0.3678 mL	0.7356 mL	3.6779 mL
20 mM	0.0368 mL	0.1839 mL	0.3678 mL	1.8390 mL
50 mM	0.0147 mL	0.0736 mL	0.1471 mL	0.7356 mL
100 mM	0.0074 mL	0.0368 mL	0.0736 mL	0.3678 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc