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Nourseothricin sulfate

Name: Nourseothricin sulfate
Brand: TargetMol
SKU: T12248
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12248Cas No. 96736-11-7

Alias Streptothricin sulfate

Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic that inhibits protein biosynthesis in prokaryotic cells and significantly impedes the growth of eukaryotes, including fungi.

Nourseothricin sulfate

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Purity: 99.83%

Catalog No. T12248Alias Streptothricin sulfateCas No. 96736-11-7

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$39	In Stock	In Stock
10 mg	$63	In Stock	In Stock
25 mg	$107	In Stock	In Stock
50 mg	$163	In Stock	In Stock
100 mg	$263	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.83%

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COA LCMS

Product Introduction

Bioactivity

Description	Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic that inhibits protein biosynthesis in prokaryotic cells and significantly impedes the growth of eukaryotes, including fungi.
In vivo	Renal handling of Nourseothricin is characterized in experiments on renal cortical slices under various experimental conditions.?Following administration in vivo the renal tubular transport system for organic anions (p-aminohippurate, PAH) is not influenced by Nourseothricin.?There is a high degree of accumulation of Nourseothricin in renal cortical slices.?In contrast to PAH accumulation there is no influence of nitrogen atmosphere, simultaneous administration of PAH, probenecid or trishydroxyaminomethane on Nourseothricin accumulation.?Age dependent differences in Nourseothricin accumulation does not exist[1].
Synonyms	Streptothricin sulfate

Chemical Properties

Molecular Weight	1359.47
Formula	C₅₀H₉₄N₂₀O₂₂S
Cas No.	96736-11-7
Smiles	OS(O)(=O)=O.[H][C@]12NC(N[C@@H]3O[C@H](CO)[C@H](OC(N)=O)[C@@H](O)[C@H]3NC(=O)C[C@@H](N)CCCNC(=O)C[C@@H](N)CCCN)=N[C@]1([H])C(=O)NC[C@H]2O
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 250 mg/mL (183.9 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	0.7356 mL	3.6779 mL	7.3558 mL	36.7790 mL
5 mM	0.1471 mL	0.7356 mL	1.4712 mL	7.3558 mL
10 mM	0.0736 mL	0.3678 mL	0.7356 mL	3.6779 mL
20 mM	0.0368 mL	0.1839 mL	0.3678 mL	1.8390 mL
50 mM	0.0147 mL	0.0736 mL	0.1471 mL	0.7356 mL
100 mM	0.0074 mL	0.0368 mL	0.0736 mL	0.3678 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc