Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Cystamine

Cystamine
Cystamine (2,2'-Disulfanediyldiethanamine) is an inhibitor of transglutaminase and inhibits caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used in studies about Huntington's diseases.
Catalog No. T15035Cas No. 51-85-4
Select Batch
Purity:99.41%
Contact us for more batch information

Resource Download

Cystamine

Catalog No. T15035Cas No. 51-85-4

Cystamine (2,2'-Disulfanediyldiethanamine) is an inhibitor of transglutaminase and inhibits caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used in studies about Huntington's diseases.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
10 mg$32In Stock
25 mg$50In Stock
50 mg$72In Stock
100 mg$98In Stock
500 mg$278In Stock
Bulk & Custom
Add to Cart

Related Compound Libraries of "Cystamine"

Product Introduction

Bioactivity
Description
Cystamine (2,2'-Disulfanediyldiethanamine) is an inhibitor of transglutaminase and inhibits caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used in studies about Huntington's diseases.
Targets&IC50
Caspase-3:23.6 μM
In vitro
In human neuroblastoma SH-SY5Y cells, Cystamine inhibits the MG132-mediated and H2O2-mediated activation of caspase-3 in a concentration-dependent manner. Cystamine (250 μM) robustly results in an increasement of the glutathione level[1].
In vivo
In R6/2 transgenic HD mice, oral and intraperitoneal administration of Cystamine (112-225 mg/kg) reduces the levels of transglutaminase and N(Sigma)-(gamma-L-glutamyl)-L-lysin. Cystamine extends survival and improves body weight and motor performance[2].
Alias2,2'-Disulfanediyldiethanamine
Chemical Properties
Molecular Weight152.28
FormulaC4H12N2S2
Cas No.51-85-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90.0 mg/mL (591.0 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.5669 mL32.8343 mL65.6685 mL328.3425 mL
5 mM1.3134 mL6.5669 mL13.1337 mL65.6685 mL
10 mM0.6567 mL3.2834 mL6.5669 mL32.8343 mL
20 mM0.3283 mL1.6417 mL3.2834 mL16.4171 mL
50 mM0.1313 mL0.6567 mL1.3134 mL6.5669 mL
100 mM0.0657 mL0.3283 mL0.6567 mL3.2834 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Cystamine | purchase Cystamine | Cystamine cost | order Cystamine | Cystamine chemical structure | Cystamine in vivo | Cystamine in vitro | Cystamine formula | Cystamine molecular weight