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F092

Name: F092
Brand: TargetMol
SKU: T69730
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T69730Cas No. 2250261-59-5

F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.

F092

🥰Excellent

Purity: 99.63%

Catalog No. T69730Cas No. 2250261-59-5

F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$48	In Stock	In Stock
5 mg	$123	In Stock	In Stock
10 mg	$185	In Stock	In Stock
25 mg	$372	In Stock	In Stock
50 mg	$596	In Stock	In Stock
100 mg	$948	In Stock	In Stock
200 mg	$1,270	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.63%

Appearance:Solid

Color:Yellow

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.
Targets&IC50	HPGDS:0.14 nM (Kd)

Chemical Properties

Molecular Weight	359.38
Formula	C₂₀H₁₇N₅O₂
Cas No.	2250261-59-5
Smiles	O=C(NC1=CC=C(C=C1)N2C(=O)CCC2)C=3C=NC(=NC3)C4=NC=CC=C4

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (278.26 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7826 mL	13.9128 mL	27.8257 mL	139.1285 mL
5 mM	0.5565 mL	2.7826 mL	5.5651 mL	27.8257 mL
10 mM	0.2783 mL	1.3913 mL	2.7826 mL	13.9128 mL
20 mM	0.1391 mL	0.6956 mL	1.3913 mL	6.9564 mL
50 mM	0.0557 mL	0.2783 mL	0.5565 mL	2.7826 mL
100 mM	0.0278 mL	0.1391 mL	0.2783 mL	1.3913 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc