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F092

Name: F092
Brand: TargetMol
SKU: T69730
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T69730Cas No. 2250261-59-5

F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.

F092

🥰Excellent

Purity: 99.63%

Catalog No. T69730Cas No. 2250261-59-5

F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.

Pack Size	Price	Availability
1 mg	$48	In Stock
5 mg	$123	In Stock
10 mg	$185	In Stock
25 mg	$372	In Stock
50 mg	$596	In Stock
100 mg	$948	In Stock
200 mg	$1,270	In Stock

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Batch Information

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Purity:99.63%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.
Targets&IC50	HPGDS:0.14 nM (Kd)

Chemical Properties

Molecular Weight	359.38
Formula	C₂₀H₁₇N₅O₂
Cas No.	2250261-59-5
Smiles	O=C(NC1=CC=C(C=C1)N2C(=O)CCC2)C=3C=NC(=NC3)C4=NC=CC=C4
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (278.26 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7826 mL	13.9128 mL	27.8257 mL	139.1285 mL
5 mM	0.5565 mL	2.7826 mL	5.5651 mL	27.8257 mL
10 mM	0.2783 mL	1.3913 mL	2.7826 mL	13.9128 mL
20 mM	0.1391 mL	0.6956 mL	1.3913 mL	6.9564 mL
50 mM	0.0557 mL	0.2783 mL	0.5565 mL	2.7826 mL
100 mM	0.0278 mL	0.1391 mL	0.2783 mL	1.3913 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc