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SKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $293 | In Stock | |
5 mg | $722 | In Stock | |
10 mg | $987 | In Stock | |
25 mg | $1,520 | In Stock | |
50 mg | $1,980 | In Stock | |
100 mg | $2,500 | In Stock |
Description | SKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro. |
Targets&IC50 | K+-stimulated ATPase:1.9 μM, Acridine orange:0.84 μM |
In vitro | In lyophilized gastric vesicles at pH 7.0, SKF96067 was found to inhibit K+-stimulated ATPase activity, in the presence of 1 mM KCl, with an IC50 value of 1.9 μM. Effects on the initial rate of acidification were monitored by the accumulation and quenching of the fluorescent dye acridine orange. SKF96067 inhibited the initial rate of acridine orange quenching with an IC50 of 0.84 μM. [1] |
Alias | SKF-96067, SKF 96067 |
Molecular Weight | 334.41 |
Formula | C21H22N2O2 |
Cas No. | 115607-61-9 |
Smiles | O=C(C1=CN=C2C(OC)=CC=CC2=C1NC=3C=CC=CC3C)CCC |
Relative Density. | 1.31g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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