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SKF96067

Name: SKF96067
Brand: TargetMol
SKU: T16894
Price: 293 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T16894Cas No. 115607-61-9

Alias SKF-96067, SKF 96067

SKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.

SKF96067

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Purity: 99.89%

Catalog No. T16894Alias SKF-96067, SKF 96067Cas No. 115607-61-9

SKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.

Pack Size	Price	Availability
1 mg	$293	In Stock
5 mg	$722	In Stock
10 mg	$987	In Stock
25 mg	$1,520	In Stock
50 mg	$1,980	In Stock
100 mg	$2,500	In Stock

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Purity:99.89%

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COA HNMR HPLC LCMS

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Product Introduction

Bioactivity

Description	SKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.
Targets&IC50	Acridine orange:0.84 μM, K+-stimulated ATPase:1.9 μM
In vitro	In lyophilized gastric vesicles at pH 7.0, SKF96067 was found to inhibit K+-stimulated ATPase activity, in the presence of 1 mM KCl, with an IC50 value of 1.9 μM. Effects on the initial rate of acidification were monitored by the accumulation and quenching of the fluorescent dye acridine orange. SKF96067 inhibited the initial rate of acridine orange quenching with an IC50 of 0.84 μM. [1]
Alias	SKF-96067, SKF 96067

Chemical Properties

Molecular Weight	334.41
Formula	C₂₁H₂₂N₂O₂
Cas No.	115607-61-9
Smiles	O=C(C1=CN=C2C(OC)=CC=CC2=C1NC=3C=CC=CC3C)CCC
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

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