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Cimicifugoside

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Catalog No. T8303Cas No. 66176-93-0

Cimicifugoside, a triterpenoid isolated from Cimicifuga simplex, is a novel, specific nucleoside transport inhibitor and exhibits immunosuppressive activity.

Cimicifugoside

Cimicifugoside

😃Good
Catalog No. T8303Cas No. 66176-93-0
Cimicifugoside, a triterpenoid isolated from Cimicifuga simplex, is a novel, specific nucleoside transport inhibitor and exhibits immunosuppressive activity.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Cimicifugoside, a triterpenoid isolated from Cimicifuga simplex, is a novel, specific nucleoside transport inhibitor and exhibits immunosuppressive activity.
Chemical Properties
Molecular Weight674.8
FormulaC37H54O11
Cas No.66176-93-0
Smiles[H][C@@]12O[C@]1(C)C(O)O[C@]21C[C@@H](C)[C@H]2[C@]([H])(C[C@@]3(C)C4=CC[C@]5([H])[C@]6(CC46C[C@H](OC(C)=O)[C@]23C)CC[C@@H](O[C@@H]2OC[C@@H](O)[C@H](O)[C@H]2O)C5(C)C)O1
Relative Density.1.38 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 100 mg/mL (148.19 mM), Sonication is recommended.
Ethanol: 100 mg/mL (148.19 mM), Sonication is recommended.
DMSO: 100 mg/mL (148.19 mM), Sonication is recommended.
Solution Preparation Table
H2O/Ethanol/DMSO
1mg5mg10mg50mg
1 mM1.4819 mL7.4096 mL14.8192 mL74.0960 mL
5 mM0.2964 mL1.4819 mL2.9638 mL14.8192 mL
10 mM0.1482 mL0.7410 mL1.4819 mL7.4096 mL
20 mM0.0741 mL0.3705 mL0.7410 mL3.7048 mL
50 mM0.0296 mL0.1482 mL0.2964 mL1.4819 mL
100 mM0.0148 mL0.0741 mL0.1482 mL0.7410 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

InhibitorinhibitCimicifugoside
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