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Azidamfenicol

Name: Azidamfenicol
Brand: TargetMol
SKU: T14391
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T14391 Copy Product Info

Purity: 99.61%

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Azidamfenicol inhibits ribosomal peptidyltransferase with a Ki of 22 µM. Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic.

Azidamfenicol

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Catalog No. T14391

Azidamfenicol inhibits ribosomal peptidyltransferase with a Ki of 22 µM. Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic.

Cas No. 13838-08-9

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Pack Size	Price	USA Stock	Global Stock
1 mg	$40	In Stock	In Stock
5 mg	$82	In Stock	In Stock
10 mg	$136	In Stock	In Stock
25 mg	$250	In Stock	In Stock
50 mg	$371	In Stock	In Stock
100 mg	$527	In Stock	In Stock
200 mg	$726	-	In Stock
1 mL x 10 mM (in DMSO)	$109	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.61%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Azidamfenicol AI Summary

Azidamfenicol has a dissociation constant (pKa) of 3.03 and demonstrates 60.0% inhibition against N-acetyl-L-[14C] phenylalanylpuromycin formation at a concentration of 8e-4 M. Additionally, it has an inhibition constant (Ki) of 22000.0 nM, as determined from Dixon and slope vs. inhibitor concentration plots..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Azidamfenicol inhibits ribosomal peptidyltransferase with a Ki of 22 µM. Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic.

Chemical Properties

Molecular Weight	295.25
Formula	C₁₁H₁₃N₅O₅
Cas No.	13838-08-9
Smiles	OC[C@@H](NC(=O)CN=[N+]=[N-])[C@H](O)c1ccc(cc1)[N+]([O-])=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (186.28 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3870 mL	16.9348 mL	33.8696 mL	169.3480 mL
5 mM	0.6774 mL	3.3870 mL	6.7739 mL	33.8696 mL
10 mM	0.3387 mL	1.6935 mL	3.3870 mL	16.9348 mL
20 mM	0.1693 mL	0.8467 mL	1.6935 mL	8.4674 mL
50 mM	0.0677 mL	0.3387 mL	0.6774 mL	3.3870 mL
100 mM	0.0339 mL	0.1693 mL	0.3387 mL	1.6935 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc