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Glutathione oxidized

Name: Glutathione oxidized
Brand: TargetMol
SKU: T1085L
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1085LCas No. 27025-41-8

Alias Oxidized glutathione, L-Glutathione oxidized, L(-)-Glutathione, GSSG, Glutathione disulfide, Bi(glutathion-S-yl)

Glutathione oxidized (L(-) -glutathione) is the oxidized form of Glutathione, which is a major antioxidant and antidote in cells. Glutathione oxidized can be used to study sickle cells and red blood cells.

Glutathione oxidized

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Purity: 99.88%

Catalog No. T1085LAlias Oxidized glutathione, L-Glutathione oxidized, L(-)-Glutathione, GSSG, Glutathione disulfide, Bi(glutathion-S-yl)Cas No. 27025-41-8

Pack Size	Price	Availability
500 mg	$39	In Stock
1 g	$47	In Stock
1 mL x 10 mM (in H2O)	$39	In Stock

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Purity:99.88%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Glutathione oxidized (L(-) -glutathione) is the oxidized form of Glutathione, which is a major antioxidant and antidote in cells. Glutathione oxidized can be used to study sickle cells and red blood cells.
Targets&IC50	[3H]AMPA:0.8-15.9 μM
In vitro	METHODS: Sickle erythrocytes were treated with Glutathione oxidized (10 μmol/L) for 0, 90, 150, and 210 minutes to detect the difference in GSH concentration between intracellular and extracellular. RESULTS: Increased efflux of Glutathione oxidized causes glutathione depletion and may impair the antioxidant defense of sickle erythrocytes. [1]
In vivo	METHODS: To study the effect of Glutathione oxidized on brain injury, Glutathione oxidized (100 mM) was injected into wild type mice. RESULTS: Glutathione oxidized causes significant brain damage in wild type mice. [2]
Synonyms	Oxidized glutathione, L-Glutathione oxidized, L(-)-Glutathione, GSSG, Glutathione disulfide, Bi(glutathion-S-yl)

Chemical Properties

Molecular Weight	612.63
Formula	C₂₀H₃₂N₆O₁₂S₂
Cas No.	27025-41-8
Smiles	[C@@H](NC(CC[C@@H](C(O)=O)N)=O)(C(NCC(O)=O)=O)CSSC[C@H](NC(CC[C@@H](C(O)=O)N)=O)C(NCC(O)=O)=O
Relative Density.	1.54g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 1.39 mg/mL (2.27 mM), Sonication is recommended.

H2O: 255 mg/mL (416.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.6323 mL	8.1615 mL	16.3231 mL	81.6153 mL

H2O

	1mg	5mg	10mg	50mg
5 mM	0.3265 mL	1.6323 mL	3.2646 mL	16.3231 mL
10 mM	0.1632 mL	0.8162 mL	1.6323 mL	8.1615 mL
20 mM	0.0816 mL	0.4081 mL	0.8162 mL	4.0808 mL
50 mM	0.0326 mL	0.1632 mL	0.3265 mL	1.6323 mL
100 mM	0.0163 mL	0.0816 mL	0.1632 mL	0.8162 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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