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Ertugliflozin

Name: Ertugliflozin
Brand: TargetMol
SKU: T4999
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T4999Cas No. 1210344-57-2

Alias PF-04971729, MK-8835

PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).

Ertugliflozin

🥰Excellent

Purity: 99.96%

Catalog No. T4999Alias PF-04971729, MK-8835Cas No. 1210344-57-2

PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).

Pack Size	Price	Availability
5 mg	$40	In Stock
10 mg	$56	In Stock
25 mg	$77	In Stock
50 mg	$97	In Stock
100 mg	$139	In Stock
500 mg	$347	In Stock
1 mL x 10 mM (in DMSO)	$44	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.96%

Resource Download

COA LCMS HNMR HPLC

Product Introduction

Bioactivity

Description	PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).
Targets&IC50	SGLT2 (human):0.877 nM
Synonyms	PF-04971729, MK-8835

Chemical Properties

Molecular Weight	436.88
Formula	C₂₂H₂₅ClO₇
Cas No.	1210344-57-2
Smiles	CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1
Relative Density.	1.455 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 260 mg/mL (595.13 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (11.44 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2890 mL	11.4448 mL	22.8896 mL	114.4479 mL
5 mM	0.4578 mL	2.2890 mL	4.5779 mL	22.8896 mL
10 mM	0.2289 mL	1.1445 mL	2.2890 mL	11.4448 mL
20 mM	0.1144 mL	0.5722 mL	1.1445 mL	5.7224 mL
50 mM	0.0458 mL	0.2289 mL	0.4578 mL	2.2890 mL
100 mM	0.0229 mL	0.1144 mL	0.2289 mL	1.1445 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc