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Detomidine hydrochloride

Name: Detomidine hydrochloride
Brand: TargetMol
SKU: T6464
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T6464Cas No. 90038-01-0

Alias MPV-253 AII, Domosedan, Detomidine HCl

Detomidine hydrochloride (MPV-253 AII) produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.

Detomidine hydrochloride

🥰Excellent

Purity: 99.97%

Catalog No. T6464Alias MPV-253 AII, Domosedan, Detomidine HClCas No. 90038-01-0

Detomidine hydrochloride (MPV-253 AII) produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.

Pack Size	Price	Availability
25 mg	$41	In Stock
50 mg	$48	In Stock
100 mg	$65	In Stock
200 mg	$93	In Stock

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Batch Information

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Purity:99.97%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Detomidine hydrochloride (MPV-253 AII) produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.
Synonyms	MPV-253 AII, Domosedan, Detomidine HCl

Chemical Properties

Molecular Weight	222.71
Formula	C₁₂H₁₄N₂·HCl
Cas No.	90038-01-0
Smiles	Cl.CC1=C(C)C(CC2=CNC=N2)=CC=C1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 42 mg/mL (188.59 mM), Sonication is recommended.

DMSO: 65 mg/mL (291.86 mM), Sonication is recommended.

H2O: 41 mg/mL (184.1 mM), Sonication is recommended.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4901 mL	22.4507 mL	44.9014 mL	224.5072 mL
5 mM	0.8980 mL	4.4901 mL	8.9803 mL	44.9014 mL
10 mM	0.4490 mL	2.2451 mL	4.4901 mL	22.4507 mL
20 mM	0.2245 mL	1.1225 mL	2.2451 mL	11.2254 mL
50 mM	0.0898 mL	0.4490 mL	0.8980 mL	4.4901 mL
100 mM	0.0449 mL	0.2245 mL	0.4490 mL	2.2451 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc