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CRAC intermediate 2

Name: CRAC intermediate 2
Brand: TargetMol
SKU: T10885
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10885Cas No. 123066-64-8

CRAC intermediate 2 is used as an intermediate compound in the synthesis of CRAC inhibitors.

CRAC intermediate 2

🥰Excellent

Purity: 99.69%

Catalog No. T10885Cas No. 123066-64-8

CRAC intermediate 2 is used as an intermediate compound in the synthesis of CRAC inhibitors.

Pack Size	Price	Availability
25 mg	$52	In Stock
50 mg	$83	In Stock
100 mg	$125	In Stock
200 mg	$183	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.69%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

CRAC intermediate 2 is used as an intermediate compound in the synthesis of CRAC inhibitors.

Chemical Properties

Molecular Weight	295.18
Formula	C₁₁H₇F₆N₃
Cas No.	123066-64-8
Smiles	NC1=CC=C(C=C1)N1N=C(C=C1C(F)(F)F)C(F)(F)F
Relative Density.	1.52 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (169.39 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3878 mL	16.9388 mL	33.8776 mL	169.3882 mL
5 mM	0.6776 mL	3.3878 mL	6.7755 mL	33.8776 mL
10 mM	0.3388 mL	1.6939 mL	3.3878 mL	16.9388 mL
20 mM	0.1694 mL	0.8469 mL	1.6939 mL	8.4694 mL
50 mM	0.0678 mL	0.3388 mL	0.6776 mL	3.3878 mL
100 mM	0.0339 mL	0.1694 mL	0.3388 mL	1.6939 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc