store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
STAT3-IN-11 is a selective STAT3 inhibitor with inhibitory effects on phosphorylation of the STAT3pTyr705 site and phosphorylation of Survivin.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 870.00 | |
50 mg | 6-8 weeks | $ 1,130.00 | |
100 mg | 6-8 weeks | $ 1,820.00 |
Description | STAT3-IN-11 is a selective STAT3 inhibitor with inhibitory effects on phosphorylation of the STAT3pTyr705 site and phosphorylation of Survivin.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer. |
In vitro | STAT3-IN-11 (2.5-10μM, 6 hours) dose-dependently inhibits phosphorylation of STAT3 at the pTyr705 site stimulated by IL-6 in MDA-MB-231 cells. However, it does not affect the phosphorylation of upstream kinases such as p-JAK2 and p-Src, nor the phosphorylation of STAT1, a STAT subtype. |
Molecular Weight | 335.35 |
Formula | C20H17NO4 |
CAS No. | 2503096-50-0 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (238.55 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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STAT3-IN-11 2503096-50-0 Apoptosis JAK/STAT signaling Stem Cells STAT inhibitor inhibit