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Idebenone

Name: Idebenone
Brand: TargetMol
SKU: T0412
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0412Cas No. 58186-27-9

Alias CV-2619

Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).

Idebenone

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Purity: 99.52%

Catalog No. T0412Alias CV-2619Cas No. 58186-27-9

Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).

Pack Size	Price	Availability
10 mg	$40	In Stock
25 mg	$55	In Stock
50 mg	$81	In Stock
100 mg	$108	In Stock
200 mg	$164	In Stock
1 mL x 10 mM (in DMSO)	$48	In Stock

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Batch Information

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Purity:99.52%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).
In vitro	Idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and consequently protects the lipid membrane and mitochondria from oxidative damage.
Synonyms	CV-2619

Chemical Properties

Molecular Weight	338.44
Formula	C₁₉H₃₀O₅
Cas No.	58186-27-9
Smiles	COC1=C(OC)C(=O)C(CCCCCCCCCCO)=C(C)C1=O
Relative Density.	1.08 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (118.19 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: 63 mg/mL (186.15 mM), Sonication is recommended.

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.9547 mL	14.7737 mL	29.5473 mL	147.7367 mL
5 mM	0.5909 mL	2.9547 mL	5.9095 mL	29.5473 mL
10 mM	0.2955 mL	1.4774 mL	2.9547 mL	14.7737 mL
20 mM	0.1477 mL	0.7387 mL	1.4774 mL	7.3868 mL
50 mM	0.0591 mL	0.2955 mL	0.5909 mL	2.9547 mL
100 mM	0.0295 mL	0.1477 mL	0.2955 mL	1.4774 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc