Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Echimidine

😃Good
Catalog No. TN3913Cas No. 520-68-3
Alias (+)-Echimidine

Echimidine ((+)-Echimidine) is a natural pyrrolizidine alkaloid and direct AChE inhibitor that also has binding activity to muscarinic receptors and 5-HT2, and can be used to study Alzheimer's disease.

Echimidine

Echimidine

😃Good
Catalog No. TN3913Alias (+)-EchimidineCas No. 520-68-3
Echimidine ((+)-Echimidine) is a natural pyrrolizidine alkaloid and direct AChE inhibitor that also has binding activity to muscarinic receptors and 5-HT2, and can be used to study Alzheimer's disease.
Pack SizePriceAvailabilityQuantity
1 mg$1,189 Backorder
Bulk & Custom
Add to Cart
Questions
View More
Select Batch
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Echimidine ((+)-Echimidine) is a natural pyrrolizidine alkaloid and direct AChE inhibitor that also has binding activity to muscarinic receptors and 5-HT2, and can be used to study Alzheimer's disease.
In vivo
Zebrafish embryos were exposed to different concentrations of Echimidine (0.02, 0.2, and 2 mg/L), and changes in the total distance traveled, average swimming speed, activity, and total movement time of the zebrafish larvae were observed. The Results showed that at the highest concentration, the total distance traveled and average swimming speed increased by 39.79% and 39.76%, respectively. Echimidine inhibited acetylcholinesterase (AChE) activity, impaired the neural development of zebrafish embryos, and induced hyperactivity in the zebrafish larvae [1].
Alias(+)-Echimidine
Chemical Properties
Molecular Weight397.46
FormulaC20H31NO7
Cas No.520-68-3
SmilesC(OC([C@]([C@@](C)(C)O)([C@H](C)O)O)=O)C=1[C@]2(N(CC[C@H]2OC(/C(=C\C)/C)=O)CC1)[H]
Relative Density.1.26 g/cm3 at 20℃
Storage & Solubility Information
Storagestore under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Echimidine | purchase Echimidine | Echimidine cost | order Echimidine | Echimidine chemical structure | Echimidine in vivo | Echimidine formula | Echimidine molecular weight