Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

Echimidine

Name: Echimidine
Brand: TargetMol
SKU: TN3913
Rating: 4.5 (1 reviews)

Copy Product Info

😃Good

Catalog No. TN3913Cas No. 520-68-3

Alias (+)-Echimidine

Echimidine ((+)-Echimidine) is a natural pyrrolizidine alkaloid and direct AChE inhibitor that also has binding activity to muscarinic receptors and 5-HT2, and can be used to study Alzheimer's disease.

Echimidine

Copy Product Info

😃Good

Catalog No. TN3913Alias (+)-EchimidineCas No. 520-68-3

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$1,189	Inquiry	Inquiry

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Appearance:Viscous

Color:Transparent

Resource Download

COA

Product Introduction

Bioactivity

Description	Echimidine ((+)-Echimidine) is a natural pyrrolizidine alkaloid and direct AChE inhibitor that also has binding activity to muscarinic receptors and 5-HT2, and can be used to study Alzheimer's disease.
In vivo	Zebrafish embryos were exposed to different concentrations of Echimidine (0.02, 0.2, and 2 mg/L), and changes in the total distance traveled, average swimming speed, activity, and total movement time of the zebrafish larvae were observed. The Results showed that at the highest concentration, the total distance traveled and average swimming speed increased by 39.79% and 39.76%, respectively. Echimidine inhibited acetylcholinesterase (AChE) activity, impaired the neural development of zebrafish embryos, and induced hyperactivity in the zebrafish larvae [1].
Synonyms	(+)-Echimidine

Chemical Properties

Molecular Weight	397.46
Formula	C₂₀H₃₁NO₇
Cas No.	520-68-3
Smiles	C(OC([C@]([C@@](C)(C)O)([C@H](C)O)O)=O)C=1[C@]2(N(CC[C@H]2OC(/C(=C\C)/C)=O)CC1)[H]
Relative Density.	1.26 g/cm3 at 20℃

Storage & Solubility Information

Storage

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc