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Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 mg | $33 | In Stock | In Stock | |
| 100 mg | $48 | In Stock | In Stock | |
| 200 mg | $60 | In Stock | In Stock | |
| 500 mg | $95 | In Stock | In Stock | |
| 1 g | $138 | - | In Stock |
| Description | Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome. |
| In vivo | Research indicates that Tiratricol can reduce thyroid enlargement and mitigate atrophy caused by decreased use of corticosteroid hormones. Furthermore, Tiratricol is effective in treating thyroid hormone resistance syndrome and, in combination with thyroxine, can suppress the production of thyroid-stimulating hormone in patients with thyroid cancer. |
| Synonyms | 3,3',5-Triiodothyroacetic acid |
| Molecular Weight | 621.93 |
| Formula | C14H9I3O4 |
| Cas No. | 51-24-1 |
| Smiles | O(C1=C(I)C=C(CC(O)=O)C=C1I)C2=CC(I)=C(O)C=C2 |
| Relative Density. | 2.466 g/cm3 |
| Storage | The compound is unstable in solution. Please use soon | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: < 1 mg/mL (insoluble or slightly soluble), The compound is unstable in solution. Please use soon. DMSO: 93 mg/mL (149.53 mM), Sonication is recommended. The compound is unstable in solution. Please use soon. Ethanol: 93 mg/mL (149.53 mM), Sonication is recommended. The compound is unstable in solution. Please use soon. | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (5.31 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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