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ALW-II-49-7

Catalog No. T67736 CAS 1135219-23-6

ALW-II-49-7 is a selective and potent inhibitor of EphB2 kinase with an EC50 value of 40 nM in cell.

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ALW-II-49-7, CAS 1135219-23-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	ALW-II-49-7 is a selective and potent inhibitor of EphB2 kinase with an EC50 value of 40 nM in cell.
In vitro	ALW-II-49-7 (0.01-10 μ M; 1 h) inhibits the activity of EphB2 kinase in U87 glioblastoma cells at a concentration of 2 μ g/mL[1].

Molecular Weight	414.38
Formula	C21H17F3N4O2
CAS No.	1135219-23-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 25 mg/mL (60.33 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Choi Y, et al. Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4467-70.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

ALW-II-49-7 1135219-23-6 Tyrosine Kinase/Adaptors Ephrin Receptor ALWII497 Inhibitor inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.