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Telekin

Name: Telekin
Brand: TargetMol
SKU: T9144
Price: 133 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9144Cas No. 6752-90-5

Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells

Telekin

🥰Excellent

Purity: 99.97%

Catalog No. T9144Cas No. 6752-90-5

Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells

Pack Size	Price	Availability
1 mg	$133	In Stock
5 mg	$302	In Stock
10 mg	$453	In Stock
25 mg	$747	In Stock
50 mg	$1,050	In Stock
1 mL x 10 mM (in DMSO)	$276	In Stock

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Batch Information

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Purity:99.97%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells
In vitro	telekin activates the mitochondria-mediated apoptotic pathway in hepatocellular carcinoma cells and may merit further investigation as a potential therapeutic agent for the treatment of hepatocellular carcinoma[1].

Chemical Properties

Molecular Weight	248.32
Formula	C₁₅H₂₀O₃
Cas No.	6752-90-5
Smiles	C[C@]12[C@@](O)(C[C@]3([C@@](C1)(OC(=O)C3=C)[H])[H])C(=C)CCC2
Relative Density.	1.16 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (110.74 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0271 mL	20.1353 mL	40.2706 mL	201.3531 mL
5 mM	0.8054 mL	4.0271 mL	8.0541 mL	40.2706 mL
10 mM	0.4027 mL	2.0135 mL	4.0271 mL	20.1353 mL
20 mM	0.2014 mL	1.0068 mL	2.0135 mL	10.0677 mL
50 mM	0.0805 mL	0.4027 mL	0.8054 mL	4.0271 mL
100 mM	0.0403 mL	0.2014 mL	0.4027 mL	2.0135 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc