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STD1T

Name: STD1T
Brand: TargetMol
SKU: T36970
Price: 199 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T36970Cas No. 893075-58-6

STD1T is a selective and potent inhibitor of the deubiquitinase USP2a with potential anticancer activity that reduces cell cycle protein D1 protein levels in HCT116 colon and MCF-7 breast cancer cells.

STD1T

🥰Excellent

Purity: 98.77%

Catalog No. T36970Cas No. 893075-58-6

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$199	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.77%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	STD1T is a selective and potent inhibitor of the deubiquitinase USP2a with potential anticancer activity that reduces cell cycle protein D1 protein levels in HCT116 colon and MCF-7 breast cancer cells.
In vitro	STD1T inhibits the enzymatic activity of USP2a in a concentration-dependent manner. It exhibits selective inhibition of USP2a compared to USP7 at concentrations of 10 µM and 2000 µM, respectively[1].

Chemical Properties

Molecular Weight	417.5
Formula	C₁₉H₁₉N₃O₄S₂
Cas No.	893075-58-6
Smiles	NC(=O)c1c(NC(=O)COCc2cc(on2)-c2cccs2)sc2CCCCc12

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (119.76 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3952 mL	11.9760 mL	23.9521 mL	119.7605 mL
5 mM	0.4790 mL	2.3952 mL	4.7904 mL	23.9521 mL
10 mM	0.2395 mL	1.1976 mL	2.3952 mL	11.9760 mL
20 mM	0.1198 mL	0.5988 mL	1.1976 mL	5.9880 mL
50 mM	0.0479 mL	0.2395 mL	0.4790 mL	2.3952 mL
100 mM	0.0240 mL	0.1198 mL	0.2395 mL	1.1976 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc