Shopping Cart

Your shopping cart is currently empty

Oligomycin

Name: Oligomycin
Brand: TargetMol
SKU: T21494
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T21494Cas No. 1404-19-9

Oligomycin is a macrolide antibiotic produced by Streptomyces. Oligomycin is commonly used to study mitochondrial function and cellular energy metabolism and has antifungal and antitumor activities.

Oligomycin

🥰Excellent

Catalog No. T21494Cas No. 1404-19-9

Oligomycin is a macrolide antibiotic produced by Streptomyces. Oligomycin is commonly used to study mitochondrial function and cellular energy metabolism and has antifungal and antitumor activities.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$42	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Resource Download

COA

Product Introduction

Bioactivity

Description	Oligomycin is a macrolide antibiotic produced by Streptomyces. Oligomycin is commonly used to study mitochondrial function and cellular energy metabolism and has antifungal and antitumor activities.
In vitro	METHODS: The OCI-AML-1 cell line, OCI-AML-5 cell line and K562 cell line were treated with Oligomycin (0.025-500 nM) for 4 days to detect the inhibition of cell growth. RESULTS: Bleomycin hydrochloride inhibited the growth of the OCI-AML-1 cell line (IC50=0.05 nM), the OCI-AML-5 cell line (IC50=0.1 nM), and the K562 cell line (IC50=0.05 nM). [1]

Chemical Properties

Molecular Weight	791.076
Formula	C₄₅H₇₄O₁₁
Cas No.	1404-19-9
Smiles	[H][C@@](C)(O)C[C@@]1([H])O[C@]2(CC[C@@]1([H])C)O[C@]1([H])CC[C@]([H])(CC)\C=C/C=C/C[C@]([H])(C)[C@@]([H])(O)[C@@](C)(O)C(=O)[C@]([H])(C)[C@@]([H])(O)[C@]([H])(C)C(=O)[C@]([H])(C)[C@@]([H])(O)[C@]([H])(C)\C=C\C(=O)O[C@@]([H])([C@@]1([H])C)[C@@]2([H])C \|c:24,t:26,60\|
Relative Density.	1.143 g/cm3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 20.00 mg/mL (25.28 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2641 mL	6.3205 mL	12.6410 mL	63.2051 mL
5 mM	0.2528 mL	1.2641 mL	2.5282 mL	12.6410 mL
10 mM	0.1264 mL	0.6321 mL	1.2641 mL	6.3205 mL
20 mM	0.0632 mL	0.3160 mL	0.6321 mL	3.1603 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc