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Benactyzine hydrochloride

Name: Benactyzine hydrochloride
Brand: TargetMol
SKU: T2571
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2571Cas No. 57-37-4

Alias Tranquilline, Neuroleptone, Amitakon

Benactyzine hydrochloride (Neuroleptone) is a centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to investigate the role of cholinergic systems on behavior.

Benactyzine hydrochloride

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Purity: 99.94%

Catalog No. T2571Alias Tranquilline, Neuroleptone, AmitakonCas No. 57-37-4

Pack Size	Price	Availability
100 mg	$41	In Stock
200 mg	$59	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Purity:99.94%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Benactyzine hydrochloride (Neuroleptone) is a centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to investigate the role of cholinergic systems on behavior.
Targets&IC50	BChE:0.010 mM(Ki)
Synonyms	Tranquilline, Neuroleptone, Amitakon

Chemical Properties

Molecular Weight	363.88
Formula	C₂₀H₂₆ClNO₃
Cas No.	57-37-4
Smiles	Cl.CCN(CC)CCOC(=O)C(O)(c1ccccc1)c1ccccc1
Relative Density.	1.115g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (164.89 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7482 mL	13.7408 mL	27.4816 mL	137.4079 mL
5 mM	0.5496 mL	2.7482 mL	5.4963 mL	27.4816 mL
10 mM	0.2748 mL	1.3741 mL	2.7482 mL	13.7408 mL
20 mM	0.1374 mL	0.6870 mL	1.3741 mL	6.8704 mL
50 mM	0.0550 mL	0.2748 mL	0.5496 mL	2.7482 mL
100 mM	0.0275 mL	0.1374 mL	0.2748 mL	1.3741 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc