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Avobenzone

Name: Avobenzone
Brand: TargetMol
SKU: T0695
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0695Cas No. 70356-09-1

Alias Butyl methoxydibenzoylmethane, BF2AVB

Avobenzone is a dibenzoylmethane endocrine disruptor that binds directly to estrogen receptor β, acting as an estrogen agonist. It is one of the most widely used filters in sunscreens for photoprotection of skin in the UV band.

Avobenzone

🥰Excellent

Purity: 97.93%

Catalog No. T0695Alias Butyl methoxydibenzoylmethane, BF2AVBCas No. 70356-09-1

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$48	In Stock	In Stock
500 mg	$68	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.93%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Avobenzone is a dibenzoylmethane endocrine disruptor that binds directly to estrogen receptor β, acting as an estrogen agonist. It is one of the most widely used filters in sunscreens for photoprotection of skin in the UV band.
Synonyms	Butyl methoxydibenzoylmethane, BF2AVB

Chemical Properties

Molecular Weight	310.39
Formula	C₂₀H₂₂O₃
Cas No.	70356-09-1
Smiles	C(CC(=O)C1=CC=C(OC)C=C1)(=O)C2=CC=C(C(C)(C)C)C=C2
Relative Density.	1.221. Temperature:20 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 9 mg/mL (29 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 75 mg/mL (241.63 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 3.3 mg/mL (10.63 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2218 mL	16.1088 mL	32.2175 mL	161.0877 mL
5 mM	0.6444 mL	3.2218 mL	6.4435 mL	32.2175 mL
10 mM	0.3222 mL	1.6109 mL	3.2218 mL	16.1088 mL
20 mM	0.1611 mL	0.8054 mL	1.6109 mL	8.0544 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0644 mL	0.3222 mL	0.6444 mL	3.2218 mL
100 mM	0.0322 mL	0.1611 mL	0.3222 mL	1.6109 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc