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5-Methoxyindole-3-acetic acid

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Catalog No. T13513Cas No. 3471-31-6
Alias Methoxyindoleacetic acid, 5-Methoxyindoleacetic acid

5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue.

5-Methoxyindole-3-acetic acid

5-Methoxyindole-3-acetic acid

🥰Excellent
Purity: 98.55%
Catalog No. T13513Alias Methoxyindoleacetic acid, 5-Methoxyindoleacetic acidCas No. 3471-31-6
5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$29In StockIn Stock
500 mg$42In StockIn Stock
1 g$58In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.55%
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COA HNMR HPLC LCMS

Product Introduction

Bioactivity
Description
5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue.
In vivo
Transplacental administration of 5-methoxyindole-3-acetic acid possessing blastomogenic activity induced the development of malignant and benign neoplasms (lymphosarcomas, adenomas, hepatomas and other tumours) in 84% of C57BL/6 mouse progeny. The number of neoplasms was significantly higher, than in the control, they appeared earlier and were more malignant[2].
SynonymsMethoxyindoleacetic acid, 5-Methoxyindoleacetic acid
Chemical Properties
Molecular Weight205.21
FormulaC11H11NO3
Cas No.3471-31-6
SmilesCOC1=CC=C2NC=C(CC(O)=O)C2=C1
Relative Density.1.2235 g/cm3 (Estimated)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 88 mg/mL (428.83 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (16.08 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.8731 mL24.3653 mL48.7306 mL243.6528 mL
5 mM0.9746 mL4.8731 mL9.7461 mL48.7306 mL
10 mM0.4873 mL2.4365 mL4.8731 mL24.3653 mL
20 mM0.2437 mL1.2183 mL2.4365 mL12.1826 mL
50 mM0.0975 mL0.4873 mL0.9746 mL4.8731 mL
100 mM0.0487 mL0.2437 mL0.4873 mL2.4365 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Keywords

InhibitorinhibitHuman Endogenous MetaboliteEndogenousMetaboliteEndogenous Metabolite5-Methoxyindole-3-acetic acid5Methoxyindole3acetic acid5 Methoxyindole 3 acetic acid
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