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5-Methoxyindole-3-acetic acid

Name: 5-Methoxyindole-3-acetic acid
Brand: TargetMol
SKU: T13513
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T13513Cas No. 3471-31-6

Alias Methoxyindoleacetic acid, 5-Methoxyindoleacetic acid

5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue.

5-Methoxyindole-3-acetic acid

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Purity: 98.55%

Catalog No. T13513Alias Methoxyindoleacetic acid, 5-Methoxyindoleacetic acidCas No. 3471-31-6

5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue.

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$29	In Stock	In Stock
500 mg	$42	In Stock	In Stock
1 g	$58	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:98.55%

Appearance:Solid

Color:White

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COA HPLC LCMS HNMR

Product Introduction

Bioactivity

Description	5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue.
In vivo	Transplacental administration of 5-methoxyindole-3-acetic acid possessing blastomogenic activity induced the development of malignant and benign neoplasms (lymphosarcomas, adenomas, hepatomas and other tumours) in 84% of C57BL/6 mouse progeny. The number of neoplasms was significantly higher, than in the control, they appeared earlier and were more malignant[2].
Synonyms	Methoxyindoleacetic acid, 5-Methoxyindoleacetic acid

Chemical Properties

Molecular Weight	205.21
Formula	C₁₁H₁₁NO₃
Cas No.	3471-31-6
Smiles	COC1=CC=C2NC=C(CC(O)=O)C2=C1
Relative Density.	1.2235 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 247.5 mg/mL (1206.08 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (16.08 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8731 mL	24.3653 mL	48.7306 mL	243.6528 mL
5 mM	0.9746 mL	4.8731 mL	9.7461 mL	48.7306 mL
10 mM	0.4873 mL	2.4365 mL	4.8731 mL	24.3653 mL
20 mM	0.2437 mL	1.2183 mL	2.4365 mL	12.1826 mL
50 mM	0.0975 mL	0.4873 mL	0.9746 mL	4.8731 mL
100 mM	0.0487 mL	0.2437 mL	0.4873 mL	2.4365 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc