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Ivermectin B1a

Name: Ivermectin B1a
Brand: TargetMol
SKU: T21727
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T21727Cas No. 71827-03-7

Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.

Ivermectin B1a

🥰Excellent

Catalog No. T21727Cas No. 71827-03-7

Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$48	In Stock	In Stock
5 mg	$123	In Stock	-
10 mg	$197	In Stock	-
25 mg	$396	In Stock	-
50 mg	$579	In Stock	-
1 mL x 10 mM (in DMSO)	$238	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:≥98%

Resource Download

COA HNMR

Product Introduction

Bioactivity

Description	Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.
In vitro	Ivermectin B1a(0.3 μg/ml) is inactive, whereas in the case of the minor component, ivermectin B1b(0.3 μg/ml) produces 100% mortality of snails[1].

Chemical Properties

Molecular Weight	875.09
Formula	C₄₈H₇₄O₁₄
Cas No.	71827-03-7
Smiles	CCC(C)C1OC2(CCC1C)CC1CC(C\C=C(C)\C(OC3CC(OC)C(OC4CC(OC)C(O)C(C)O4)C(C)O3)C(C)\C=C\C=C3/COC4C(O)C(C)=CC(C(=O)O1)C34O)O2
Relative Density.	1.0683 g/cm3 (Estimated)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (114.27 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (4.57 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1427 mL	5.7137 mL	11.4274 mL	57.1370 mL
5 mM	0.2285 mL	1.1427 mL	2.2855 mL	11.4274 mL
10 mM	0.1143 mL	0.5714 mL	1.1427 mL	5.7137 mL
20 mM	0.0571 mL	0.2857 mL	0.5714 mL	2.8568 mL
50 mM	0.0229 mL	0.1143 mL	0.2285 mL	1.1427 mL
100 mM	0.0114 mL	0.0571 mL	0.1143 mL	0.5714 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc