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Casein kinase 1δ-IN-5

Name: Casein kinase 1δ-IN-5
Brand: TargetMol
SKU: T79154
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T79154Cas No. 1579991-10-8

Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor (IC50 = 47 nM) that exhibits neuroprotective and anti-inflammatory effects in vitro, with potential applications in neurodegenerative disease research.

Casein kinase 1δ-IN-5

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Purity: 99.62%

Catalog No. T79154Cas No. 1579991-10-8

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$38	-	In Stock
5 mg	$60	-	In Stock
10 mg	$98	-	In Stock
25 mg	$193	-	In Stock
50 mg	$286	-	In Stock
100 mg	$426	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.62%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor (IC50 = 47 nM) that exhibits neuroprotective and anti-inflammatory effects in vitro, with potential applications in neurodegenerative disease research.
Targets&IC50	CK1δ:47 nM

Chemical Properties

Molecular Weight	336.33
Formula	C₁₆H₁₁F₃N₂OS
Cas No.	1579991-10-8
Smiles	C(F)(F)(F)C=1C=C2C(N=C(NC(CC3=CC=CC=C3)=O)S2)=CC1
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc