Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the caveolae-mediated endocytosis inhibitor genistein . It is cytotoxic to H1299 cells (IC50 = 88.5 μg/ml).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 78.00 | |
5 mg | 35 days | $ 273.00 | |
10 mg | 35 days | $ 460.00 |
Description | Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the caveolae-mediated endocytosis inhibitor genistein . It is cytotoxic to H1299 cells (IC50 = 88.5 μg/ml). |
Molecular Weight | 884.059 |
Formula | C43H71F6N5O7 |
CAS No. | 1609010-56-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 50 mg/mL
DMSO: 50 mg/mL
Ethanol: 50 mg/mL
Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
You can also refer to dose conversion for different animals. More
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Cho-Arg (trifluoroacetate salt) 1609010-56-1 Cho Arg (trifluoroacetate salt) ChoArg (trifluoroacetate salt) Cho-Arg inhibitor inhibit