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MFCD28987368

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Catalog No. T8924Cas No. 1610413-97-2

MFCD28987368 is a degradable ADC linker that can be used in the synthesis of antibody coupled drugs (ADCs).

MFCD28987368

MFCD28987368

🥰Excellent
Purity: 95.15%
Catalog No. T8924Cas No. 1610413-97-2
MFCD28987368 is a degradable ADC linker that can be used in the synthesis of antibody coupled drugs (ADCs).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$30In StockIn Stock
5 mg$36In StockIn Stock
10 mg$55In StockIn Stock
25 mg$98In StockIn Stock
50 mg$147In StockIn Stock
100 mg$221In StockIn Stock
1 mL x 10 mM (in DMSO)$58In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:95.15%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
MFCD28987368 is a degradable ADC linker that can be used in the synthesis of antibody coupled drugs (ADCs).
Chemical Properties
Molecular Weight678.81
FormulaC34H54N4O10
Cas No.1610413-97-2
SmilesCC(C)(C)OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)NCc1ccc(CC(O)=O)cc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C
Relative Density.1.156 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (88.39 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4732 mL7.3658 mL14.7317 mL73.6583 mL
5 mM0.2946 mL1.4732 mL2.9463 mL14.7317 mL
10 mM0.1473 mL0.7366 mL1.4732 mL7.3658 mL
20 mM0.0737 mL0.3683 mL0.7366 mL3.6829 mL
50 mM0.0295 mL0.1473 mL0.2946 mL1.4732 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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