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MFCD28987368

🥰Excellent
Catalog No. T8924Cas No. 1610413-97-2

MFCD28987368 is a degradable ADC linker that can be used in the synthesis of antibody coupled drugs (ADCs).

MFCD28987368

MFCD28987368

🥰Excellent
Purity: 95.15%
Catalog No. T8924Cas No. 1610413-97-2
MFCD28987368 is a degradable ADC linker that can be used in the synthesis of antibody coupled drugs (ADCs).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$50In StockIn Stock
5 mg$60In StockIn Stock
10 mg$91In StockIn Stock
25 mg$163In StockIn Stock
50 mg$245In StockIn Stock
100 mg$369In StockIn Stock
1 mL x 10 mM (in DMSO)$97In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:95.15%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
MFCD28987368 is a degradable ADC linker that can be used in the synthesis of antibody coupled drugs (ADCs).
Chemical Properties
Molecular Weight678.81
FormulaC34H54N4O10
Cas No.1610413-97-2
SmilesCC(C)(C)OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)NCc1ccc(CC(O)=O)cc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C
Relative Density.1.156 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (88.39 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4732 mL7.3658 mL14.7317 mL73.6583 mL
5 mM0.2946 mL1.4732 mL2.9463 mL14.7317 mL
10 mM0.1473 mL0.7366 mL1.4732 mL7.3658 mL
20 mM0.0737 mL0.3683 mL0.7366 mL3.6829 mL
50 mM0.0295 mL0.1473 mL0.2946 mL1.4732 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MFCD-28987368MFCD28987368MFCD 28987368InhibitorinhibitAntibody-drug conjugates linkersADCLinkerADC LinkersADC Linker
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