Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

MYX1715

Name: MYX1715
Brand: TargetMol
SKU: T88528
Rating: 4.5 (1 reviews)

(Synonyms: MYX 1715, IMP-1320, IMP1320) Copy Product Info

🥰Excellent

Synonyms: MYX 1715, IMP-1320, IMP1320

Catalog No. T88528 Copy Product Info

🥰Excellent

MYX1715 is an inhibitor of N-myristoyltransferase (NMT) with a KD value of 0.09 nM. MYX1715 inhibits the proliferation of LU0884 and LU2511 cells with IC50 values of 44 nM and 9 nM, respectively. In mouse models, MYX1715 demonstrates antitumor activity against neuroblastoma and gastric cancer. Additionally, MYX1715 can be utilized as a toxin component in antibody-drug conjugates (ADCs). The potent N-myristoyltransferase inhibitory activity of MYX1715 supports the application of MYX1715 in cancer biology research, protein lipidation studies, targeted delivery platform development, and investigations of N-myristoyltransferase-dependent cellular processes.

Cas No. 2445448-66-6

Pack Size	Price	USA Stock	Global Stock
25 mg	$4,000	10-14 weeks	10-14 weeks
50 mg	$5,430	10-14 weeks	10-14 weeks
100 mg	$7,660	10-14 weeks	10-14 weeks

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

Product Introduction

Bioactivity

Description

Synonyms

MYX 1715, IMP-1320, IMP1320

Chemical Properties

Molecular Weight	480.99
Formula	C₂₅H₂₉ClN₆O₂
Cas No.	2445448-66-6
Smiles	O=C(C1=NN(C(=C1CCOC=2C=C(Cl)C=CC2C=3C=CC4=NC=C(N4C3)CCN)C)C)N(C)C

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (207.9 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0790 mL	10.3952 mL	20.7905 mL	103.9523 mL
5 mM	0.4158 mL	2.0790 mL	4.1581 mL	20.7905 mL
10 mM	0.2079 mL	1.0395 mL	2.0790 mL	10.3952 mL
20 mM	0.1040 mL	0.5198 mL	1.0395 mL	5.1976 mL
50 mM	0.0416 mL	0.2079 mL	0.4158 mL	2.0790 mL
100 mM	0.0208 mL	0.1040 mL	0.2079 mL	1.0395 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: MYX1715 chemical structure | MYX1715 formula | MYX1715 molecular weight