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DOTATATE acetate

Name: DOTATATE acetate
Brand: TargetMol
SKU: T39193
Price: 64 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T39193 Copy Product Info

Purity: 98.70%

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DOTATATE acetate is a DOTA-binding peptide, a growth inhibitor analog, and a novel PET tracer involved in the assessment of functional imaging of highly differentiated neuroendocrine tumors (NETs).

DOTATATE acetate

Copy Product Info

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Catalog No. T39193

DOTATATE acetate is a DOTA-binding peptide, a growth inhibitor analog, and a novel PET tracer involved in the assessment of functional imaging of highly differentiated neuroendocrine tumors (NETs).

Cas No. 177943-89-4

Pack Size	Price	USA Stock	Global Stock
1 mg	$64	In Stock	In Stock
5 mg	$198	In Stock	In Stock
10 mg	$347	In Stock	In Stock
25 mg	$619	In Stock	In Stock
50 mg	$887	-	In Stock
100 mg	$1,190	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:98.70%

Appearance:Solid

Color:White

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COA LCMS

Product Introduction

Bioactivity

Description	DOTATATE acetate is a DOTA-binding peptide, a growth inhibitor analog, and a novel PET tracer involved in the assessment of functional imaging of highly differentiated neuroendocrine tumors (NETs).
In vivo	Dotatate acetate exhibits high affinity and specificity, allowing it to bind to and activate the somatostatin receptor subtype 2 (SSTR2) effectively, thereby inhibiting tumor cell proliferation and differentiation[1].

Chemical Properties

Molecular Weight	1495.69
Formula	C₆₇H₉₄N₁₄O₂₁S₂
Cas No.	177943-89-4
Smiles	C(C)(O)=O.C(C=1C=2C(NC1)=CC=CC2)[C@H]3NC(=O)[C@H](CC4=CC=C(O)C=C4)NC(=O)[C@@H](NC([C@@H](CC5=CC=CC=C5)NC(CN6CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC6)=O)=O)CSSC[C@@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCCCN)NC3=O)[H]
Relative Density.	no data available
Sequence	{DOTA}-{d-Phe}-CY-{d-Trp}-KTCT (Disulfide bridge:Cys2-Cys7)

Storage & Solubility Information

Storage

keep away from moisture,store under nitrogen,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 5.00 mg/mL (3.34 mM), Sonication is recommended.

DMSO: 80.00 mg/mL (53.49 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	0.6686 mL	3.3429 mL	6.6859 mL	33.4294 mL

DMSO

	1mg	5mg	10mg	50mg
5 mM	0.1337 mL	0.6686 mL	1.3372 mL	6.6859 mL
10 mM	0.0669 mL	0.3343 mL	0.6686 mL	3.3429 mL
20 mM	0.0334 mL	0.1671 mL	0.3343 mL	1.6715 mL
50 mM	0.0134 mL	0.0669 mL	0.1337 mL	0.6686 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc