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Eg5 Inhibitor V, trans-24

Name: Eg5 Inhibitor V, trans-24
Brand: TargetMol
SKU: T11155
Price: 93 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T11155Cas No. 869304-55-2

Eg5 Inhibitor V, trans-24, is a specific and potent Eg5 inhibitor with an IC50 value of 0.65 μM, suitable for use in cancer research.

Eg5 Inhibitor V, trans-24

🥰Excellent

Purity: 99.75%

Catalog No. T11155Cas No. 869304-55-2

Eg5 Inhibitor V, trans-24, is a specific and potent Eg5 inhibitor with an IC50 value of 0.65 μM, suitable for use in cancer research.

Pack Size	Price	Availability
1 mg	$93	In Stock
5 mg	$215	In Stock
10 mg	$322	In Stock
25 mg	$520	In Stock
50 mg	$713	In Stock
100 mg	$953	In Stock
200 mg	$1,280	In Stock
1 mL x 10 mM (in DMSO)	$239	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.75%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Eg5 Inhibitor V, trans-24, is a specific and potent Eg5 inhibitor with an IC50 value of 0.65 μM, suitable for use in cancer research.
Targets&IC50	EG5:0.65 μM
In vitro	Trans-24 is a potent EG5-specific inhibitor with an IC50 conversion rate of 0.65 M and can be used in cancer research[1].

Chemical Properties

Molecular Weight	423.46
Formula	C₂₆H₂₁N₃O₃
Cas No.	869304-55-2
Smiles	[H][C@@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)N(Cc1ccccc1)C2=O)c1cccc(O)c1
Relative Density.	1.47 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (106.27 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3615 mL	11.8075 mL	23.6150 mL	118.0749 mL
5 mM	0.4723 mL	2.3615 mL	4.7230 mL	23.6150 mL
10 mM	0.2361 mL	1.1807 mL	2.3615 mL	11.8075 mL
20 mM	0.1181 mL	0.5904 mL	1.1807 mL	5.9037 mL
50 mM	0.0472 mL	0.2361 mL	0.4723 mL	2.3615 mL
100 mM	0.0236 mL	0.1181 mL	0.2361 mL	1.1807 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc