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Kansuinine A

Name: Kansuinine A
Brand: TargetMol
SKU: TN4379
Price: 167 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN4379Cas No. 57701-86-7

Kansuinine A, a 95% ethanol extract from the roots of E. kansui, possesses an inhibitory effect on IL-6-induced Stat3 activation by activating ERK1/2.

Kansuinine A

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Purity: 99.28%

Catalog No. TN4379Cas No. 57701-86-7

Kansuinine A, a 95% ethanol extract from the roots of E. kansui, possesses an inhibitory effect on IL-6-induced Stat3 activation by activating ERK1/2.

Pack Size	Price	Availability
1 mg	$167	In Stock
5 mg	$412	In Stock
10 mg	$613	In Stock
25 mg	$977	In Stock
50 mg	$1,320	Backorder
1 mL x 10 mM (in DMSO)	$663	In Stock

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Purity:99.28%

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COA HPLC

Product Introduction

Bioactivity

Description	Kansuinine A, a 95% ethanol extract from the roots of E. kansui, possesses an inhibitory effect on IL-6-induced Stat3 activation by activating ERK1/2.
In vitro	Kansuinine A markedly promoted SPL proliferation and NO production by PMphi at concentrations from 0.78 to 12.50 microg/mL[3].

Chemical Properties

Molecular Weight	730.75
Formula	C₃₇H₄₆O₁₅
Cas No.	57701-86-7
Smiles	[H][C@]12O[C@](O)([C@H](C)C1=O)[C@]1(C[C@H](C)[C@H](OC(C)=O)[C@]1([H])[C@@H](OC(C)=O)C(=C)[C@H](OC(C)=O)[C@@H](OC(=O)c1ccccc1)[C@@H](OC(C)=O)C2(C)C)OC(C)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: ≥ 100 mg/mL (136.85 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (2.74 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3685 mL	6.8423 mL	13.6846 mL	68.4229 mL
5 mM	0.2737 mL	1.3685 mL	2.7369 mL	13.6846 mL
10 mM	0.1368 mL	0.6842 mL	1.3685 mL	6.8423 mL
20 mM	0.0684 mL	0.3421 mL	0.6842 mL	3.4211 mL
50 mM	0.0274 mL	0.1368 mL	0.2737 mL	1.3685 mL
100 mM	0.0137 mL	0.0684 mL	0.1368 mL	0.6842 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc