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Angelic anhydride

Name: Angelic anhydride
Brand: TargetMol
SKU: TWS1293
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TWS1293Cas No. 94487-74-8

Alias 2-Methylisocrotonic Anhydride, (Z)-2-Methylbut-2-enoic anhydride

Angelic anhydride ((Z)-2-Methylbut-2-enoic anhydride) is a reagent in the improved synthesis of angelate esters, which are the active chemical behind the strong pain-relieving and spasmolytic action of extracts from the plant butterbur.

Angelic anhydride

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Purity: 99.7%

Catalog No. TWS1293Alias 2-Methylisocrotonic Anhydride, (Z)-2-Methylbut-2-enoic anhydrideCas No. 94487-74-8

Pack Size	Price	Availability	Quantity
20 mg	$50	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Batch Information

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Purity:99.7%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Angelic anhydride ((Z)-2-Methylbut-2-enoic anhydride) is a reagent in the improved synthesis of angelate esters, which are the active chemical behind the strong pain-relieving and spasmolytic action of extracts from the plant butterbur.
Synonyms	2-Methylisocrotonic Anhydride, (Z)-2-Methylbut-2-enoic anhydride

Chemical Properties

Molecular Weight	182.22
Formula	C₁₀H₁₄O₃
Cas No.	94487-74-8
Smiles	C\C=C(\C)C(=O)OC(=O)C(\C)=C/C
Relative Density.	1.02 g/cm3
Color	Transparent
Appearance	Liquid

Storage & Solubility Information

Storage

High Volatility | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

DMSO: 70 mg/mL (384.15 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.4879 mL	27.4394 mL	54.8787 mL	274.3936 mL
5 mM	1.0976 mL	5.4879 mL	10.9757 mL	54.8787 mL
10 mM	0.5488 mL	2.7439 mL	5.4879 mL	27.4394 mL
20 mM	0.2744 mL	1.3720 mL	2.7439 mL	13.7197 mL
50 mM	0.1098 mL	0.5488 mL	1.0976 mL	5.4879 mL
100 mM	0.0549 mL	0.2744 mL	0.5488 mL	2.7439 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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