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Desogestrel

Name: Desogestrel
Brand: TargetMol
SKU: T6819
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T6819Cas No. 54024-22-5

Alias Org-2969, Desogestrelum, Desogen, Cerazette

Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.

Desogestrel

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Purity: 99.8%

Catalog No. T6819Alias Org-2969, Desogestrelum, Desogen, CerazetteCas No. 54024-22-5

Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$38	In Stock	In Stock
50 mg	$68	In Stock	In Stock
100 mg	$103	In Stock	In Stock
200 mg	$155	-	In Stock
1 mL x 10 mM (in DMSO)	$31	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.8%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
In vivo	Desogestrel is extensively metabolized after oral administration to rats and dogs; In rats, desogestrel is metabolized mainly at the C3, C5, C11, and C15 positions. An hydroxy group is introduced at the 15α-position of desogestrel, followed by conjugation with glucuronic acid. In dogs, desogestrel is mainly metabolized at the C3- and C17-positions[1].
Synonyms	Org-2969, Desogestrelum, Desogen, Cerazette

Chemical Properties

Molecular Weight	310.47
Formula	C₂₂H₃₀O
Cas No.	54024-22-5
Smiles	[H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC(=C)[C@]1([H])[C@@]3([H])CCCC=C3CC[C@@]21[H]
Relative Density.	1.07 g/cm3

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 58 mg/mL (186.81 mM), Sonication is recommended.

DMSO: 58 mg/mL (186.81 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.22 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2209 mL	16.1046 mL	32.2092 mL	161.0462 mL
5 mM	0.6442 mL	3.2209 mL	6.4418 mL	32.2092 mL
10 mM	0.3221 mL	1.6105 mL	3.2209 mL	16.1046 mL
20 mM	0.1610 mL	0.8052 mL	1.6105 mL	8.0523 mL
50 mM	0.0644 mL	0.3221 mL	0.6442 mL	3.2209 mL
100 mM	0.0322 mL	0.1610 mL	0.3221 mL	1.6105 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc