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Desogestrel

Name: Desogestrel
Brand: TargetMol
SKU: T6819
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T6819Cas No. 54024-22-5

Alias Org-2969, Desogestrelum, Desogen, Cerazette

Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.

Desogestrel

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Purity: 99.8%

Catalog No. T6819Alias Org-2969, Desogestrelum, Desogen, CerazetteCas No. 54024-22-5

Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.

Pack Size	Price	Availability
25 mg	$38	In Stock
50 mg	$68	In Stock
100 mg	$103	In Stock
200 mg	$155	In Stock
1 mL x 10 mM (in DMSO)	$31	In Stock

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Batch Information

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Purity:99.8%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
In vivo	Desogestrel is extensively metabolized after oral administration to rats and dogs; In rats, desogestrel is metabolized mainly at the C3, C5, C11, and C15 positions. An hydroxy group is introduced at the 15α-position of desogestrel, followed by conjugation with glucuronic acid. In dogs, desogestrel is mainly metabolized at the C3- and C17-positions[1].
Synonyms	Org-2969, Desogestrelum, Desogen, Cerazette

Chemical Properties

Molecular Weight	310.47
Formula	C₂₂H₃₀O
Cas No.	54024-22-5
Smiles	[H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC(=C)[C@]1([H])[C@@]3([H])CCCC=C3CC[C@@]21[H]
Relative Density.	1.07 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 58 mg/mL (186.81 mM), Sonication is recommended.

DMSO: 58 mg/mL (186.81 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.22 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2209 mL	16.1046 mL	32.2092 mL	161.0462 mL
5 mM	0.6442 mL	3.2209 mL	6.4418 mL	32.2092 mL
10 mM	0.3221 mL	1.6105 mL	3.2209 mL	16.1046 mL
20 mM	0.1610 mL	0.8052 mL	1.6105 mL	8.0523 mL
50 mM	0.0644 mL	0.3221 mL	0.6442 mL	3.2209 mL
100 mM	0.0322 mL	0.1610 mL	0.3221 mL	1.6105 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc