Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent inhibitor of steroid sulfatase (STS). Estrone O-sulfamate is a placental microsomal inhibitor (P.M.) with IC50 values of 18 nM. Estrone O-sulfamate showed inhibitory effects on STS in MCF-7 cells with IC50 values of 0.83 nM. Estrone O-sulfamate can be used to study cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 397.00 | |
5 mg | In stock | $ 970.00 | |
10 mg | In stock | $ 1,180.00 | |
25 mg | In stock | $ 1,580.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | In stock | $ 2,500.00 |
Description | Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent inhibitor of steroid sulfatase (STS). Estrone O-sulfamate is a placental microsomal inhibitor (P.M.) with IC50 values of 18 nM. Estrone O-sulfamate showed inhibitory effects on STS in MCF-7 cells with IC50 values of 0.83 nM. Estrone O-sulfamate can be used to study cancer. |
Targets&IC50 | STS (MCF-7 cells):0.83 nM, STS (P.M.):18 nM |
In vitro | In both placental microsome (P.M.) preparations and MCF-7 cells, Estrone O-sulfamate (Estrone 3-O-sulfamate) exhibits inhibitory activity against STS, with IC50 values of 18 nM and 0.83 nM, respectively[1]. |
Synonyms | Estrone 3-O-sulfamate |
Molecular Weight | 349.44 |
Formula | C18H23NO4S |
CAS No. | 148672-09-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (157.39 mM)
You can also refer to dose conversion for different animals. More
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Estrone O-sulfamate 148672-09-7 Others Estrone 3-O-sulfamate inhibitor inhibit