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SM-7368

Name: SM-7368
Brand: TargetMol
SKU: T22115
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T22115Cas No. 380623-76-7

The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.

SM-7368

🥰Excellent

Purity: 99.64%

Catalog No. T22115Cas No. 380623-76-7

The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.

Pack Size	Price	Availability
5 mg	$39	In Stock
10 mg	$68	In Stock
25 mg	$137	In Stock
50 mg	$198	In Stock
100 mg	$297	In Stock
200 mg	$433	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.64%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.

Chemical Properties

Molecular Weight	328.69
Formula	C₁₀H₅ClN₄O₅S
Cas No.	380623-76-7
Smiles	[O-][N+](=O)c1cnc(NC(=O)c2ccc(c(Cl)c2)[N+]([O-])=O)s1
Relative Density.	1.761 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (152.12 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0424 mL	15.2119 mL	30.4238 mL	152.1190 mL
5 mM	0.6085 mL	3.0424 mL	6.0848 mL	30.4238 mL
10 mM	0.3042 mL	1.5212 mL	3.0424 mL	15.2119 mL
20 mM	0.1521 mL	0.7606 mL	1.5212 mL	7.6060 mL
50 mM	0.0608 mL	0.3042 mL	0.6085 mL	3.0424 mL
100 mM	0.0304 mL	0.1521 mL	0.3042 mL	1.5212 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc