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Ensulizole

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Catalog No. T19310Cas No. 27503-81-7
Alias Phenylbenzimidazole sulfonic acid, 2-PHENYLBENZIMIDAZOLE-5-SULFONIC ACID, 2-Phenyl-1H-benzo[d]imidazole-5-sulfonic acid

Ensulizole is a sulfonated ultraviolet absorber that strongly absorbs UVB and some UVA, and under UV or sunlight exposure, it produces reactive oxygen species that can damage DNA.

Ensulizole

Ensulizole

😃Good
Purity: 99.79%
Catalog No. T19310Alias Phenylbenzimidazole sulfonic acid, 2-PHENYLBENZIMIDAZOLE-5-SULFONIC ACID, 2-Phenyl-1H-benzo[d]imidazole-5-sulfonic acidCas No. 27503-81-7
Ensulizole is a sulfonated ultraviolet absorber that strongly absorbs UVB and some UVA, and under UV or sunlight exposure, it produces reactive oxygen species that can damage DNA.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$29-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.79%
Appearance:solid
Color:White
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Product Introduction

Bioactivity
Description
Ensulizole is a sulfonated ultraviolet absorber that strongly absorbs UVB and some UVA, and under UV or sunlight exposure, it produces reactive oxygen species that can damage DNA.
In vitro
At 4.0 mM [H2O2]0, a complete removal of 40.0 μM parent PBSA and 25% decrease in TOC are achieved with 190 min of UV irradiation.
SynonymsPhenylbenzimidazole sulfonic acid, 2-PHENYLBENZIMIDAZOLE-5-SULFONIC ACID, 2-Phenyl-1H-benzo[d]imidazole-5-sulfonic acid
Chemical Properties
Molecular Weight274.30
FormulaC13H10N2O3S
Cas No.27503-81-7
SmilesOS(=O)(=O)c1ccc2[nH]c(nc2c1)-c1ccccc1
Relative Density.1.62. Temperature:20 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
0.1 M NaOH: 9 mg/mL (32.81 mM), when pH is adjusted to 8 with NaOH. Sonication is recommended.
DMSO: 3.64 mg/mL (13.27 mM), Sonication is recommended.
Solution Preparation Table
DMSO/0.1 M NaOH
1mg5mg10mg50mg
1 mM3.6456 mL18.2282 mL36.4564 mL182.2822 mL
5 mM0.7291 mL3.6456 mL7.2913 mL36.4564 mL
10 mM0.3646 mL1.8228 mL3.6456 mL18.2282 mL
0.1 M NaOH
1mg5mg10mg50mg
20 mM0.1823 mL0.9114 mL1.8228 mL9.1141 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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