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Chlorhexidine diacetate

Name: Chlorhexidine diacetate
Brand: TargetMol
SKU: T1000L
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1000LCas No. 56-95-1

Alias Hibitane diacetate, Chlorhexidine Acetate, Bactigras

Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

Chlorhexidine diacetate

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Purity: 99.69%

Catalog No. T1000LAlias Hibitane diacetate, Chlorhexidine Acetate, BactigrasCas No. 56-95-1

Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

Pack Size	Price	USA Warehouse	Global Warehouse
500 mg	$40	In Stock	In Stock
1 g	$56	In Stock	In Stock
5 g	$113	-	In Stock
10 g	$159	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.69%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Chlorhexidine diacetate AI Summary

Chlorhexidine diacetate exhibits antimicrobial activity against various strains including Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, and Candida albicans, with potent inhibitory effects indicated by low Minimum Inhibitory Concentration (MIC) values, suggesting potential effectiveness in treating bacterial and fungal infections. Moreover, Chlorhexidine diacetate demonstrates varied bioactivities; it acts as an agonist for estrogen receptor alpha, androgen receptor, peroxisome proliferator-activated receptor gamma, the NF-kB signaling pathway, and the p53 signaling pathway, while also functioning as an antagonist for thyroid hormone receptor beta, estrogen receptor alpha, peroxisome proliferator-activated receptor delta, glucocorticoid receptor, and retinoid X receptor alpha. Additionally, it shows agonistic activity on the antioxidant response element (ARE) signaling pathway..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
Synonyms	Hibitane diacetate, Chlorhexidine Acetate, Bactigras

Chemical Properties

Molecular Weight	625.55
Formula	C₂₆H₃₈Cl₂N₁₀O₄
Cas No.	56-95-1
Smiles	c1(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(cc2)Cl)ccc(cc1)Cl.C(=O)(C)O.C(=O)(C)O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (399.65 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5986 mL	7.9930 mL	15.9859 mL	79.9297 mL
5 mM	0.3197 mL	1.5986 mL	3.1972 mL	15.9859 mL
10 mM	0.1599 mL	0.7993 mL	1.5986 mL	7.9930 mL
20 mM	0.0799 mL	0.3996 mL	0.7993 mL	3.9965 mL
50 mM	0.0320 mL	0.1599 mL	0.3197 mL	1.5986 mL
100 mM	0.0160 mL	0.0799 mL	0.1599 mL	0.7993 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc