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Quinine

🥰Excellent
Catalog No. T0690Cas No. 130-95-0

Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy has been associated with rare instances of hypersensitivity reactions which can be accompanied by hepatitis and mild jaundice.

Quinine
Other Forms of Quinine:

Quinine

🥰Excellent
Purity: 99.97%
Catalog No. T0690Cas No. 130-95-0
Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy has been associated with rare instances of hypersensitivity reactions which can be accompanied by hepatitis and mild jaundice.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$31-In Stock
5 g$63-In Stock
1 mL x 10 mM (in DMSO)$39In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.97%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy has been associated with rare instances of hypersensitivity reactions which can be accompanied by hepatitis and mild jaundice.
Targets&IC50
K+ channel:169 μM
Chemical Properties
Molecular Weight324.42
FormulaC20H24N2O2
Cas No.130-95-0
Smiles[H][C@@]12CCN(C[C@@H]1C=C)[C@@H](C2)[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1
Relative Density.>= 110 - <= 140 kg/m3.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (154.12 mM), Sonication is recommended.
H2O: Insoluble
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.16 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0824 mL15.4121 mL30.8242 mL154.1212 mL
5 mM0.6165 mL3.0824 mL6.1648 mL30.8242 mL
10 mM0.3082 mL1.5412 mL3.0824 mL15.4121 mL
20 mM0.1541 mL0.7706 mL1.5412 mL7.7061 mL
50 mM0.0616 mL0.3082 mL0.6165 mL3.0824 mL
100 mM0.0308 mL0.1541 mL0.3082 mL1.5412 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Slo3QuininePotassiumChannelPotassium ChannelpotassiumPlateletaggregationPlatelet glycoprotein IXPlatelet aggregationParasiteKcsAKCa5.1Inhibitorinhibitchannelanti-malaria
Related Tags: buy Quinine | purchase Quinine | Quinine cost | order Quinine | Quinine chemical structure | Quinine formula | Quinine molecular weight
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