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Allylthiourea

Name: Allylthiourea
Brand: TargetMol
SKU: T0418
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0418Cas No. 109-57-9

Alias Thiosinamine, N-Allylthiourea

Allylthiourea (Thiosinamine), a metabolic inhibitor, specifically suppresses ammonia oxidation.

Allylthiourea

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Purity: 99.68%

Catalog No. T0418Alias Thiosinamine, N-AllylthioureaCas No. 109-57-9

Allylthiourea (Thiosinamine), a metabolic inhibitor, specifically suppresses ammonia oxidation.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 g	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.68%

Appearance:Solid

Color:White to Yellow

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Allylthiourea (Thiosinamine), a metabolic inhibitor, specifically suppresses ammonia oxidation.
In vivo	At a concentration of 1 μM, allylthiourea inhibits 80% of ammonia oxidation; selective inhibition of ammonia oxidation occurs at concentrations ranging from 8-80 μM; at a concentration of 86 μM, allylthiourea achieves complete inhibition of ammonia oxidation.
Synonyms	Thiosinamine, N-Allylthiourea

Chemical Properties

Molecular Weight	116.18
Formula	C₄H₈N₂S
Cas No.	109-57-9
Smiles	N(C(N)=S)CC=C
Relative Density.	1.11 g/cm3 at 25℃ (lit.)

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (473.4 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: 22 mg/mL (189.36 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (17.21 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	8.6073 mL	43.0367 mL	86.0733 mL	430.3667 mL
5 mM	1.7215 mL	8.6073 mL	17.2147 mL	86.0733 mL
10 mM	0.8607 mL	4.3037 mL	8.6073 mL	43.0367 mL
20 mM	0.4304 mL	2.1518 mL	4.3037 mL	21.5183 mL
50 mM	0.1721 mL	0.8607 mL	1.7215 mL	8.6073 mL
100 mM	0.0861 mL	0.4304 mL	0.8607 mL	4.3037 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc