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CDK-IN-9

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Catalog No. T62235

CDK-IN-9 (compound 24) is a potent inhibitor of CDK and acts on CDK2/E (IC50: 4 nM). It functions as a molecular gel that induces interaction between CDK12 and DDB1, and can dephosphorylate retinoblastoma protein and RNA polymerase II, thereby inducing apoptosis.

CDK-IN-9

CDK-IN-9

😃Good
Catalog No. T62235
CDK-IN-9 (compound 24) is a potent inhibitor of CDK and acts on CDK2/E (IC50: 4 nM). It functions as a molecular gel that induces interaction between CDK12 and DDB1, and can dephosphorylate retinoblastoma protein and RNA polymerase II, thereby inducing apoptosis.
Pack SizePriceAvailabilityQuantity
25 mg$1,520 10-14 weeks
50 mg$1,980 10-14 weeks
100 mg$2,500 10-14 weeks
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Product Introduction

Bioactivity
Description
CDK-IN-9 (compound 24) is a potent inhibitor of CDK and acts on CDK2/E (IC50: 4 nM). It functions as a molecular gel that induces interaction between CDK12 and DDB1, and can dephosphorylate retinoblastoma protein and RNA polymerase II, thereby inducing apoptosis.
Targets&IC50
CDK9-CyclinT1:20 nM, CDK12/Cyclin K:64 nM, Cdk5/p25:39 nM, CDK13/Cyclin K:22 nM, CDK2-CyclinE:4 nM
Chemical Properties
Molecular Weight420.53
FormulaC21H24N8S
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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